Query：
学者姓名：夏晓峰
Refining：
Year
Type
Indexed by
Source
Complex
Co-Author
Language
Clean All
Abstract ：
The escalating demand for sustainable and eco-friendly pest management strategies has raised interest in harnessing the pathogenic potential of microorganisms. Serratia marcescens, a Gram-negative bacterium, has emerged as a potential biological control agent for sustainable pest management. This review critically examines the history, biology, identification, and pathogenicity of S. marcescens strain with their potential application in pest management. The diverse mechanisms employed by the strain to exert control over pests, including the production of metabolites and the induction of systemic resistance in plants, are examined. The review also summarizes the ecological significance and global distribution of S. marcescens associated with the use of S. marcescens in biological control strategies. Furthermore, the usage efficacy of S. marcescens over other conventional chemicals is discussed. A comprehensive understanding of the pathogenic potential of S. marcescens strains as biological control agents is crucial for developing effective and sustainable pest management strategies. This review consolidates current research advances on S. marcescens, and provides insights into the prospects and challenges of using S. marcescens for integrated pest management.
Keyword ：
biological control biological control bio-pesticides bio-pesticides Serratia marcescens Serratia marcescens sustainable pest management sustainable pest management
Cite：
Copy from the list or Export to your reference management。
| GB/T 7714 | Akhtar, Muhammad Rehan , Younas, Muhammad , Xia, Xiaofeng . Pathogenicity of Serratia marcescens strains as biological control agent: Implications for sustainable pest management [J]. | INSECT SCIENCE , 2025 . |
| MLA | Akhtar, Muhammad Rehan 等. "Pathogenicity of Serratia marcescens strains as biological control agent: Implications for sustainable pest management" . | INSECT SCIENCE (2025) . |
| APA | Akhtar, Muhammad Rehan , Younas, Muhammad , Xia, Xiaofeng . Pathogenicity of Serratia marcescens strains as biological control agent: Implications for sustainable pest management . | INSECT SCIENCE , 2025 . |
| Export to | NoteExpress RIS BibTex |
Version ：
Abstract ：
Spatzle is an important messenger in the Toll pathway of the insect innate immune system. However, the function of Spatzle in regulating the Toll pathway in Bacillus thuringiensis (Bt) susceptibility of Plutella xylostella is unclear. In this study, we cloned the Spatzle3 gene of P. xylostella. Molecular docking and yeast two-hybrid experiments indicated that PxSpatzle3 combined with PxToll6 to regulate the Toll pathway. After knocking out PxSpatzle3, the expression of downstream Toll pathway genes and antimicrobial peptides (AMPs) decreased. Antibacterial assays showed that PxGloverin2 could inhibit Bt8010. Further bioassays revealed that the susceptibility of the mutant to Bt8010 was significantly higher than that of the wild type. Intriguingly, the gut bacteria Enterobacter sp. EbPXG5 enhanced the lethality of Bt8010 to the mutant P. xylostella. Our findings clarify that PxSpatzle3 activates the Toll pathway by binding with PxToll6, regulates AMP production, and affects the susceptibility of P. xylostella to Bt8010. Additionally, our study uncovers the role of gut bacteria in this process. These insights provide new ideas for the sustainable control of pests.
Keyword ：
antimicrobial peptides antimicrobial peptides Bacillus thuringiensis Bacillus thuringiensis innate immunity innate immunity Plutella xylostella Plutella xylostella Spatzle Spatzle Tollpathway Tollpathway
Cite：
Copy from the list or Export to your reference management。
| GB/T 7714 | Sun, Yan , Yuan, Ji , Han, Shuncai et al. PxSpatzle3 Regulates the Toll Pathway To Affect Bacillus thuringiensis Susceptibility of Plutella xylostella [J]. | JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY , 2025 , 73 (9) : 5129-5139 . |
| MLA | Sun, Yan et al. "PxSpatzle3 Regulates the Toll Pathway To Affect Bacillus thuringiensis Susceptibility of Plutella xylostella" . | JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 73 . 9 (2025) : 5129-5139 . |
| APA | Sun, Yan , Yuan, Ji , Han, Shuncai , Wang, Qiuping , Akhtar, Muhammad Rehan , Xia, Xiaofeng . PxSpatzle3 Regulates the Toll Pathway To Affect Bacillus thuringiensis Susceptibility of Plutella xylostella . | JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY , 2025 , 73 (9) , 5129-5139 . |
| Export to | NoteExpress RIS BibTex |
Version ：
Abstract ：
The insect NF-kappa B pathway is primarily constituted by nuclear factor kappa B (NF-kappa B) and the inhibitor of kappa B (I kappa B), which plays a crucial role in the innate immune response. Dorsal and Cactus, as NF-kappa B and I kappa B factors, are important downstream regulators of the Toll pathway in Plutella xylostella. In this study, the PxDorsal and PxCactus genes of P. xylostella were cloned, and the molecular docking demonstrated that PxDorsal and PxCactus can interact with each other. RT-qPCR results indicated that PxDorsal and PxCactus were expressed in all stages, and the expression of PxDorsal, PxCactus, and antimicrobial peptides PxGloverin2, PxMoricin3, and PxLysozyme2 were significantly down-regulated under Bacillus thuringiensis (Bt8010) infection. Interestingly, silencing the PxDorsal gene by RNA interference (RNAi) significantly down-regulated the expression of PxGloverin2 and PxMoricin3 and increased the epidermis melanization of P. xylostella larvae fed with Bt8010. Our findings indicate that PxDorsal and PxCactus may interact with each other, and silencing PxDorsal inhibits the expression of downstream antimicrobial peptides, thereby enhance the susceptibility of P. xylostella to Bt8010. This study contributes a theoretical basis for further research on the Toll pathway of P. xylostella to pathogens and offers insights for screening effective biological control targets from the perspective of the immune system.
Keyword ：
antimicrobial peptides antimicrobial peptides Cactus Cactus Dorsal Dorsal NF-kappa B pathway NF-kappa B pathway Plutella xylostella Plutella xylostella Toll pathway Toll pathway
Cite：
Copy from the list or Export to your reference management。
| GB/T 7714 | Sun, Yan , Wen, Haoqi , Xue, Wenrui et al. PxDorsal Regulates the Expression of Antimicrobial Peptides and Affects the Bt Susceptibility of Plutella xylostella [J]. | INSECTS , 2025 , 16 (2) . |
| MLA | Sun, Yan et al. "PxDorsal Regulates the Expression of Antimicrobial Peptides and Affects the Bt Susceptibility of Plutella xylostella" . | INSECTS 16 . 2 (2025) . |
| APA | Sun, Yan , Wen, Haoqi , Xue, Wenrui , Xia, Xiaofeng . PxDorsal Regulates the Expression of Antimicrobial Peptides and Affects the Bt Susceptibility of Plutella xylostella . | INSECTS , 2025 , 16 (2) . |
| Export to | NoteExpress RIS BibTex |
Version ：
Abstract ：
本发明涉及微生物领域，本发明提出了一株贝莱斯芽孢杆菌20‑1及其应用，所述贝莱斯芽孢杆菌20‑1于2024年07月26日保藏于中国典型培养物保藏中心，保藏编号为CCTCCNO:M 20241694。本发明的贝莱斯芽孢杆菌20‑1能够有效抑制常见水生病原真菌的生长，且具有较强的热稳定性和蛋白酶耐性，可用于预防、缓解和/或治疗水生病原真菌感染引起的疾病。
Cite：
Copy from the list or Export to your reference management。
| GB/T 7714 | 夏晓峰 , 江浦滋 , 沈载芸 et al. 一株贝莱斯芽孢杆菌20-1及其应用 : CN202411995132.2[P]. | 2024-12-31 . |
| MLA | 夏晓峰 et al. "一株贝莱斯芽孢杆菌20-1及其应用" : CN202411995132.2. | 2024-12-31 . |
| APA | 夏晓峰 , 江浦滋 , 沈载芸 , 曹成全 , 魏博 , 石静雅 et al. 一株贝莱斯芽孢杆菌20-1及其应用 : CN202411995132.2. | 2024-12-31 . |
| Export to | NoteExpress RIS BibTex |
Version ：
Abstract ：
本发明涉及发酵液纯化技术领域，本发明提出了贝莱斯芽孢杆菌发酵液提取物及其应用。具体地，本发明提出了一种纯化发酵液的方法，该方法包括：1)使用萃取剂将贝莱斯芽孢杆菌发酵上清液进行萃取处理，以获得发酵液粗提物；2)使用乙醇对所述发酵液粗提物进行第一纯化处理，以获得第一纯化发酵液。本发明的纯化发酵液的方法能够有效的将发酵液中的有效成份进行纯化，纯化后的发酵液能够有效的抑制水生病原真菌活性，可用于预防、缓解和/或治疗水生病原真菌感染引起的疾病。
Cite：
Copy from the list or Export to your reference management。
| GB/T 7714 | 夏晓峰 , 江浦滋 , 沈载芸 et al. 贝莱斯芽孢杆菌发酵提取物及其应用 : CN202411995182.0[P]. | 2024-12-31 . |
| MLA | 夏晓峰 et al. "贝莱斯芽孢杆菌发酵提取物及其应用" : CN202411995182.0. | 2024-12-31 . |
| APA | 夏晓峰 , 江浦滋 , 沈载芸 , 曹成全 , 羊光辉 , 石静雅 et al. 贝莱斯芽孢杆菌发酵提取物及其应用 : CN202411995182.0. | 2024-12-31 . |
| Export to | NoteExpress RIS BibTex |
Version ：
Abstract ：
BACKGROUND Insect gut bacterial communities dynamically respond to host physiology and mediate key functions, yet a holistic view of how Plutella xylostella (a devastating cruciferous pest) gut bacteria shift across developmental stages, sexes, and mating statuses remains unclear. This study applied DNA/RNA-based 16S rRNA sequencing to capture high-resolution dynamics of its gut microbiota and decode functional correlations.RESULTS Phylum-level structure of P. xylostella stayed stable across both sequencing methods (Proteobacteria and Firmicutes as dominants). The top 50 high-abundance bacterial genera annotated by both methods are also consistent, while RNA-based 16S rRNA sequencing reveals that a greater count of high-abundance bacteria exhibited vibrant, physiological state-driven shifts: Eggs thrived with Streptococcus and Enhydrobacter. Larvae boasted the highest diversity (fueled by active feeding, with Ruminococcus, Prevotella may aid cellulose digestion in fed 1st-instars and Massilia, Comamonas may boost breakdown of hard-to-digest food in 4th-instars). Pupae dropped to the lowest diversity (a 'reset' stage, may rely on Enterobacter for energy metabolism). Non-feeding adults had peaking Bifidobacterium and Sphingomonas (may support immune regulation). Feeding adults saw Klebsiella flourish. Sex dimorphism was striking: Males had consistent Delftia enrichment (may enhance pathogen resistance) across stages; females showed stage-specific biases. Mating triggered marked shifts: the abundances of Lactobacillus and Faecalibacterium accumulated in mated females, potentially related to reproduction.CONCLUSION P. xylostella gut bacteria form a dynamically adaptive community, with taxa may flexibly tune to developmental, sexual, and mating demands, which is of great significance for understanding the association between the gut microbiota and their host. (c) 2025 Society of Chemical Industry.
Keyword ：
different physiological states different physiological states dynamic changes dynamic changes gut bacteria gut bacteria Plutella xylostella Plutella xylostella potential functions potential functions
Cite：
Copy from the list or Export to your reference management。
| GB/T 7714 | Han, Shuncai , Tang, Yang , Sun, Yan et al. Dynamic changes and functional analysis of gut bacteria in Plutella xylostella under different physiological conditions [J]. | PEST MANAGEMENT SCIENCE , 2025 . |
| MLA | Han, Shuncai et al. "Dynamic changes and functional analysis of gut bacteria in Plutella xylostella under different physiological conditions" . | PEST MANAGEMENT SCIENCE (2025) . |
| APA | Han, Shuncai , Tang, Yang , Sun, Yan , Lu, Yukun , Xue, Wenrui , Xia, Xiaofeng . Dynamic changes and functional analysis of gut bacteria in Plutella xylostella under different physiological conditions . | PEST MANAGEMENT SCIENCE , 2025 . |
| Export to | NoteExpress RIS BibTex |
Version ：
Abstract ：
The insect gut is a complicated ecosystem that inhabits a large number of symbiotic bacteria. As an important organ of the host insect, the symbiotic bacteria of the insect gut play very important roles in regulating physiological and metabolic processes. Recently, much progress has been made in the study of symbiotic bacteria in insect guts with the development of high-throughput sequencing technology and molecular biology. This review summarizes the primary functions of symbiotic bacteria in insect guts, such as enhancing insecticide resistance, facilitating food digestion, promoting detoxification, and regulating mating behavior and egg hatching. It also addresses some possible pathways of gut bacteria symbiont regulation governed by external habitats, physiological conditions and immunity of the host insect. This review provides solid foundations for further studies on novel theories, new technologies and practical applications of symbiotic bacteria in insect guts. (c) 2024 Society of Chemical Industry. Insect gut bacteria exhibit diverse functions, including promoting host resistance to pesticides, activating host immunity, and influencing host growth and development. Conversely, environmental factors, host developmental stages, and host immune systems can also impact the bacterial flora of guts in hosts. image
Keyword ：
gut bacterial symbionts gut bacterial symbionts hologenome hologenome host plant specialization host plant specialization immunity immunity insecticide resistance insecticide resistance
Cite：
Copy from the list or Export to your reference management。
| GB/T 7714 | Han, Shuncai , Akhtar, Muhammad Rehan , Xia, Xiaofeng . Functions and regulations of insect gut bacteria [J]. | PEST MANAGEMENT SCIENCE , 2024 , 80 (10) : 4828-4840 . |
| MLA | Han, Shuncai et al. "Functions and regulations of insect gut bacteria" . | PEST MANAGEMENT SCIENCE 80 . 10 (2024) : 4828-4840 . |
| APA | Han, Shuncai , Akhtar, Muhammad Rehan , Xia, Xiaofeng . Functions and regulations of insect gut bacteria . | PEST MANAGEMENT SCIENCE , 2024 , 80 (10) , 4828-4840 . |
| Export to | NoteExpress RIS BibTex |
Version ：
Abstract ：
The diamondback moth (DBM), Plutella xylostella, has successfully adapted to the potent chemical defenses of Brassicaceae plants that deter most other herbivores. Gut bacteria are increasingly recognized as key to the biology of many species but their role in DBM adaptation to plant defense compounds is not well known. In this study, the secondary metabolites of radish seedlings, rich in flavonoids, were identified by liquid chromatography-mass spectrometry. These secondary metabolites reduced the larval growth of DBM lacking gut bacteria. The effect was rapidly eclipsed by the re-introduction of gut microbiota, which was dominated by Enterobacter (Proteobacteria). Similarly, while treatment with the flavonoid kaempferol adversely affected growth and extended the development time, these were alleviated by the re-introduction of Enterobacter sp. EbPXG5 (EbPXG5) to the DBM gut. EbPXG5 not only degrades kaempferol both in vitro and DBM gut, but is also shown to colonize the gut epithelium, forming a protective biofilm. Genomic sequencing of EbPXG5 showed that metabolic genes were the most abundant, especially those involved in xenobiotic degradation, and the metabolism of terpenoids and polyketides, which could participate in the degradation of plant secondary metabolites such as kaempferol. Overall, our results showed that EbPXG5 is a bacterium common in the gut of DBM larvae and has the in vitro and in vivo capacity to detoxify a major secondary metabolite that is produced in brassica plants as a defense against herbivores. This insect-bacterial association may be an important contributor to the status of DBM as a major pest of brassica crops worldwide.
Keyword ：
co-evolution co-evolution gut bacteria gut bacteria herbivorous insect herbivorous insect kaempferol kaempferol Plutella xylostella Plutella xylostella secondary metabolites secondary metabolites
Cite：
Copy from the list or Export to your reference management。
| GB/T 7714 | Xia, Xiaofeng , Wang, Qian , Gurr, Geoff M. et al. Gut bacteria mediated adaptation of diamondback moth, Plutella xylostella, to secondary metabolites of host plants [J]. | MSYSTEMS , 2023 , 8 (6) . |
| MLA | Xia, Xiaofeng et al. "Gut bacteria mediated adaptation of diamondback moth, Plutella xylostella, to secondary metabolites of host plants" . | MSYSTEMS 8 . 6 (2023) . |
| APA | Xia, Xiaofeng , Wang, Qian , Gurr, Geoff M. , Vasseur, Liette , Han, Shuncai , You, Minsheng . Gut bacteria mediated adaptation of diamondback moth, Plutella xylostella, to secondary metabolites of host plants . | MSYSTEMS , 2023 , 8 (6) . |
| Export to | NoteExpress RIS BibTex |
Version ：
Abstract ：
Protohermes xanthodes (Megaloptera, Corydalidae, Protohermes), widespread species in China, is an important insects treated as food and medicine for aquaculture. In this study, the gut microbiota was investigated by 16S rRNA microbial profiling. A total of 600 Amplicon Sequence Variants (ASV) were identified, Proteobacteria and Firmicutes were the main dominant phyla, and 27 genera ran through the entire digestive tract, mainly Hafnia-Obesumbacterium (Proteobacteria), Lactobacillus and Lactococcus (Firmicutes). The PICRUSt2 functional prediction of gut microbiota showed that the foregut abundant pathways related to metabolism, environmental information processing, and genetic information processing. while the midgut had the most abundant metabolic and environmental information processing pathways, including the prominent phosphotransferase system (PTS), propionate metabolism, and & beta;-lactam resistance. The hindgut had the weakest metabolic function, but its genetic information processing was more abundant than the foregut and midgut. Additionally, 26 strains of bacteria were isolated from the midgut microorganisms, with Firmicutes being the dominant bacteria, and some of the purified bacteria had potential probiotic and anti-pathogen functions. These findings suggest that there are differences in the microorganisms of the different gut floras of the larvae, and each flora has specific metabolic functions. This research could be used to further understand the function of gut microorganisms, explore the co-evolution of P. xanthodes and gut microorganisms, and promote healthy breeding based on gut microorganisms.
Keyword ：
function prediction function prediction gut microorganism gut microorganism Megaloptera Megaloptera Protohermes xanthodes Protohermes xanthodes
Cite：
Copy from the list or Export to your reference management。
| GB/T 7714 | Shen, Zaiyun , Cao, Chengquan , Xia, Xiaofeng . Gut microbial diversity and function analysis of the final-instar larvae of Protohermes xanthodes (Megaloptera: Corydalidae) [J]. | JOURNAL OF INSECT SCIENCE , 2023 , 23 (4) . |
| MLA | Shen, Zaiyun et al. "Gut microbial diversity and function analysis of the final-instar larvae of Protohermes xanthodes (Megaloptera: Corydalidae)" . | JOURNAL OF INSECT SCIENCE 23 . 4 (2023) . |
| APA | Shen, Zaiyun , Cao, Chengquan , Xia, Xiaofeng . Gut microbial diversity and function analysis of the final-instar larvae of Protohermes xanthodes (Megaloptera: Corydalidae) . | JOURNAL OF INSECT SCIENCE , 2023 , 23 (4) . |
| Export to | NoteExpress RIS BibTex |
Version ：
Abstract ：
Simple Summary Plutella xylostella is a major pest of Cruciferae vegetables all over the world. Gut bacteria play an important role in the life activities of P. xylostella, but so far, little is known about the source and transmission of gut bacteria of P. xylostella. Therefore, we used the traditional microbial culture method to show that there is a potential correlation between the gut bacteria of P. xylostella and food bacteria, and P. xylostella gut bacteria exhibit vertical and horizontal transmission through eggs. Our research results will contribute to biological pest control based on gut bacteria. Plutella xylostella (L.), commonly known as the diamondback moth, is currently a major worldwide pest. Gut bacteria play an important role in the physiology and insecticide resistance of P. xylostella, but little is known about the sources and transmission routes of its gut bacteria. In this study, traditional microbial culture methods were used to analyze the sources and transmission modes of gut bacteria in P. xylostella, which could help develop pest control strategies based on gut bacteria. The main findings are as follows: gut bacterial diversity was significantly higher in P. xylostella-fed radish sprouts than those fed an artificial diet, indicating a potential association between gut bacteria and food bacteria. In addition, sequence analysis revealed the isolation of Enterobacter sp., Pantoea sp., Cedecea sp., and Pseudomonas sp. from both radish sprouts and P. xylostella. Importantly, Enterobacter sp. was found in all tested samples (radish sprouts, gut of P. xylostella, ovaries, and eggs), suggesting that bacteria acquired from food could be transferred from the gut to the ovaries and eggs. This was confirmed through experiments, which also showed that eggs could carry bacteria and transmit them to the gut, indicating vertical transmission of gut bacteria via eggs. Furthermore, the 3rd instar larvae of P. xylostella with and without gut bacteria were mixed and raised until the 4th instar. Then, we found that all the gut of the 4th instar larvae carried the same bacteria, indicating that the gut bacteria of P. xylostella can be horizontally transmitted through social behavior. This study lays a foundation for further exploration of the sources, transmission, and coevolution of the host of gut bacteria in P. xylostella, and provides new insights into pest control strategies based on the source and transmission of gut bacteria.
Keyword ：
gut bacteria gut bacteria Plutella xylostella Plutella xylostella source source transmission mode transmission mode
Cite：
Copy from the list or Export to your reference management。
| GB/T 7714 | Han, Shuncai , Ai, Qianqian , Xia, Xiaofeng . Potential Source and Transmission Pathway of Gut Bacteria in the Diamondback Moth, Plutella xylostella [J]. | INSECTS , 2023 , 14 (6) . |
| MLA | Han, Shuncai et al. "Potential Source and Transmission Pathway of Gut Bacteria in the Diamondback Moth, Plutella xylostella" . | INSECTS 14 . 6 (2023) . |
| APA | Han, Shuncai , Ai, Qianqian , Xia, Xiaofeng . Potential Source and Transmission Pathway of Gut Bacteria in the Diamondback Moth, Plutella xylostella . | INSECTS , 2023 , 14 (6) . |
| Export to | NoteExpress RIS BibTex |
Version ：
Export
| Results： |
Selected to |
| Format： |
