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学者姓名：刘庆华
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Abstract ：
肠道黏膜屏障是维持机体肠道稳态平衡和阻碍病原菌入侵的重要屏障，包括物理屏障、化学屏障、微生物屏障和免疫屏障4个部分，其结构和功能的完整性对维持动物肠道健康至关重要。肠道黏膜屏障损伤会导致肠道功能紊乱，影响机体健康。植物黄酮醇是自然界分布最广的类黄酮，越来越多的研究表明，黄酮醇具有调节肠道功能、减轻肠道炎症和抗氧化等作用。针对槲皮素和山奈酚两种典型的植物黄酮醇对动物肠道黏膜屏障生理调控作用及对畜禽动物的影响进行了综述，旨在为植物黄酮醇作为功能性饲料添加剂应用于畜禽养殖提供依据。
Keyword ：
山奈酚 山奈酚 植物黄酮醇 植物黄酮醇 槲皮素 槲皮素 畜禽 畜禽 肠道黏膜屏障 肠道黏膜屏障
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| GB/T 7714 | 张洁 , 李康乐 , 付馨乐 et al. 两种植物黄酮醇对动物肠道黏膜屏障的调控 [J]. | 福建农林大学学报(自然科学版) , 2025 , 54 (02) : 230-237 . |
| MLA | 张洁 et al. "两种植物黄酮醇对动物肠道黏膜屏障的调控" . | 福建农林大学学报(自然科学版) 54 . 02 (2025) : 230-237 . |
| APA | 张洁 , 李康乐 , 付馨乐 , 张冶秋 , 梁焰晖 , 刘庆华 et al. 两种植物黄酮醇对动物肠道黏膜屏障的调控 . | 福建农林大学学报(自然科学版) , 2025 , 54 (02) , 230-237 . |
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This study aims to investigate the effects of dietary supplementation with different concentrations of oligofructose (FOS) on growth performance, antioxidant capacity, immunity, and intestinal microbial composition in growing rabbits. One hundred female Dehua black rabbits (34 d of age) were randomly assigned to four groups (CON, FOS-1, FOS-2, and FOS-3), with twenty-five rabbits in each group. The CON group received only a basal diet, while the FOS-1/FOS-2/FOS-3 group received the diet supplemented with 0.3%/0.6%/0.9% FOS, respectively. The trial period lasted for 72 days. Our results revealed that FOS supplementation could improve the growing performance of rabbits and decrease the feed/gain ratio. FOS significantly enhanced serum antioxidant enzyme (SOD) and total antioxidant capacity (T-AOC) while reducing malondialdehyde (MDA). The levels of plasmic immunoglobulin (IgG, IgA, and IgM) and intestinal immune factors (IL-1 alpha, IL-2, and sIgA) were significantly improved with the FOS supplement. Additionally, FOS can improve intestinal morphology and enhance the activity of intestinal enzymes, including cellulase, lipase, and protease. Furthermore, FOS supplementation influenced the composition of intestinal microflora by increasing the abundance of Lachnospiraceae_NK4A136_group (barrier-enhancing) and Monoglobus (fiber-degrading). In conclusion, the addition of FOS has a positive impact on the growth performance, antioxidant capacity, immunity, and intestinal health of growing rabbits. The optimal dietary addition for rabbits was identified as 0.6% oligofructose.
Keyword ：
antioxidant capacity antioxidant capacity immunity immunity intestinal health intestinal health oligofructose oligofructose rabbits rabbits
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| GB/T 7714 | Qin, Liwen , Xiao, Chunlong , Shi, Menglei et al. Effects of Oligofructose Supplementation on Growth Performance, Antioxidant Capacity, Immunity, and Intestinal Health in Growing Rabbits [J]. | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , 2025 , 26 (17) . |
| MLA | Qin, Liwen et al. "Effects of Oligofructose Supplementation on Growth Performance, Antioxidant Capacity, Immunity, and Intestinal Health in Growing Rabbits" . | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 26 . 17 (2025) . |
| APA | Qin, Liwen , Xiao, Chunlong , Shi, Menglei , He, Lu , Du, Yifei , Lin, Lifan et al. Effects of Oligofructose Supplementation on Growth Performance, Antioxidant Capacity, Immunity, and Intestinal Health in Growing Rabbits . | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , 2025 , 26 (17) . |
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本发明属于微生物技术领域，具体涉及一株能提高动物肠道健康的植物乳杆菌、培养物和菌剂及其应用。所述植物乳杆菌QZF于2024年07月22日保藏于中国微生物菌种保藏管理委员会普通微生物中心，保藏编号为CGMCC No. 31389。本发明创制基于植物乳杆菌的微生态制剂，并研发适用于猪场的固/液态发酵模式，提高动物肠道健康、促进饲料资源高效利用，提高养殖效益；在妊娠母猪上的应用，可以提高母猪的肠道健康度，缩短产程，同时通过母子传递的形式，提高刚出生仔猪的肠道健康，协助幼龄仔猪建立平衡的肠道菌群，减少仔猪断奶应激。
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| GB/T 7714 | 叶长川 , 刘庆华 . 一株能提高动物肠道健康的植物乳杆菌、培养物和菌剂及其应用 : CN202510218823.X[P]. | 2025-02-26 . |
| MLA | 叶长川 et al. "一株能提高动物肠道健康的植物乳杆菌、培养物和菌剂及其应用" : CN202510218823.X. | 2025-02-26 . |
| APA | 叶长川 , 刘庆华 . 一株能提高动物肠道健康的植物乳杆菌、培养物和菌剂及其应用 : CN202510218823.X. | 2025-02-26 . |
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本试验旨在探究巨菌草替代不同水平基础饲粮对育肥从江香猪生长性能及肠道健康的影响。选取6月龄体重相近的健康从江香猪30头，随机分为3组（每组5个重复，每个重复2头）。对照组饲喂100%基础饲粮，试验Ⅰ、Ⅱ组分别用新鲜青绿巨菌草替代10%、20%基础饲粮，试验期90 d。通过测定育肥从江香猪生长性能、肠道发育、肠道机械屏障和盲肠菌群结构，并进行经济效益分析，为巨菌草在猪的生产应用中提供理论依据。本试验主要结果如下：1）生长性能：与对照组相比，试验Ⅰ、Ⅱ组育肥从江香猪生长性能及胴体性状各指标无显著差异（P>0.05）。巨菌草不计成本时，与对照组相比，试验Ⅰ组的增重成本降低8.73%，试验Ⅱ组降低11.59%；巨菌草按市场价格0.35元·kg-1计算时，试验Ⅰ组的增重成本降低2.78%，试验Ⅱ组增加1.35%。2）肠道发育：与对照组相比，试验Ⅰ、Ⅱ组育肥从江香猪胃的相对重量显著提高（P<0.05），小肠相对重量有升高的趋势（P=0.092）。与对照组相比，试验Ⅰ组育肥从江香猪回肠隐窝深度显著降低（P<0.05），回肠绒毛高度/隐窝深度（V/C）、空肠GLP-2和回肠IGF-1R基因表达量显著提高（P<0.05）；试验Ⅱ组育肥从江香猪回肠绒毛高度、V/C及空肠GLP-2基因表达量显著提高（P<0.05）。3）肠道免疫及机械屏障：与对照组相比，试验Ⅰ、Ⅱ组育肥从江香猪回肠IFN-γ含量显著降低，试验Ⅱ组空肠TGF-β含量显著提高（P<0.05）；试验Ⅰ、Ⅱ组回肠ZO-1基因表达量显著提高，试验Ⅱ组空肠Occludin基因表达量显著提高（P<0.05）。4）盲肠微生物区系：与对照组相比，试验Ⅰ、Ⅱ组育肥从江香猪Shannon指数显著提高，链球菌属相对丰度显著下降（P<0.05）。试验Ⅰ组和试验Ⅱ组毛螺菌科未分类菌属有上升趋势（P=0.065），螺旋体门（P=0.085）、密螺旋体属（P=0.085）有下降趋势。综上所述，巨菌草替代部分基础饲粮对育肥从江香猪生长性能、胴体性状无显著影响，但可提高经济效益并促进胃肠道的发育，提升肠道屏障功能，有利于肠道健康。巨菌草不计成本时，替代20%基础饲粮为宜，巨菌草按市场价格0.35元·kg-1计算时，替代10%基础饲粮为宜。
Keyword ：
巨菌草 巨菌草 生长性能 生长性能 盲肠菌群 盲肠菌群 肠道健康 肠道健康 育肥从江香猪 育肥从江香猪
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| GB/T 7714 | 张敏 , 杨锐 , 黄逸州 et al. 巨菌草对育肥从江香猪生长性能及肠道健康的影响 [J]. | 草业学报 , 2025 , 34 (05) : 171-188 . |
| MLA | 张敏 et al. "巨菌草对育肥从江香猪生长性能及肠道健康的影响" . | 草业学报 34 . 05 (2025) : 171-188 . |
| APA | 张敏 , 杨锐 , 黄逸州 , 林芷昕 , 郑贤跃 , 刘庆华 et al. 巨菌草对育肥从江香猪生长性能及肠道健康的影响 . | 草业学报 , 2025 , 34 (05) , 171-188 . |
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Introduction In modern intensive animal husbandry, weaned rabbits frequently face disrupted intestinal barrier function and impaired weight gain which triggered by weaning stress. To solve this problem sustainably, innovative and effective nutritional regulation strategies should be developed. As feed additives, compound probiotics could improve feed conversion ratio and animal intestinal health and thus gain increasing recognition. Three dominant strains (Lactobacillus plantarum QZF, Bacillus velezensis BD and Cyberlindnera fabianii EMS) were isolated from silage and combined to form different compound probiotics. In this study, we evaluated the effect of compound probiotic on growth performance, immune function, antioxidant capacity and intestinal microbiota in weaned rabbits.Methods A total of 64 weaned New Zealand rabbits were randomly divided into four groups. The CON group was fed a basal diet. Three treatment groups were established by supplying the following probiotics: SP Group, L. plantarum QZF (108 CFU/d); DP1 Group, L. plantarum QZF (108 CFU/d) and C. fabianii EMS (107 CFU/d); DP2 Group: L. plantarum QZF (108 CFU/d) and B. velezensis BD (108 CFU/d).Results and discussion Our results showed that dietary supplementation with probiotic significantly promoted growth performance (e.g., increased average daily gain and decreased feed-to-gain ratio), enhanced immune function (reflected by elevated plasmic immunoglobulin levels and reduced pro-inflammatory cytokine concentrations) and improved antioxidant capacity (manifested by higher activities of superoxide dismutase and glutathione peroxidase and lower malondialdehyde content) in weaned rabbits. Furthermore, compound probiotic supplementation influenced the composition of intestinal microflora by decreasing the abundance of Fusobacteriota (disease-related) and increasing the abundance of Christensenellaceae_R-7_group. Supplementation with compound probiotic can alter the abundance of specific gut microbiota to maintain a healthy microbial community. In conclusion, this study demonstrates that probiotics (especially compound probiotics) serve as a valuable nutritional strategy for alleviating weaning stress, optimizing growth performance and maintaining intestinal microbiota homeostasis in weaned rabbits, providing theoretical support for the application of compound probiotics in rabbit production
Keyword ：
compound probiotic compound probiotic growth performance growth performance gut microbiota gut microbiota immunity immunity weaned rabbits weaned rabbits
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| GB/T 7714 | Ye, Changchuan , Shi, Menglei , Ren, Jingnan et al. Effects of compound probiotics on growth performance, immunity, antioxidant capacity and gut microbiota in weaned rabbits [J]. | FRONTIERS IN VETERINARY SCIENCE , 2025 , 12 . |
| MLA | Ye, Changchuan et al. "Effects of compound probiotics on growth performance, immunity, antioxidant capacity and gut microbiota in weaned rabbits" . | FRONTIERS IN VETERINARY SCIENCE 12 (2025) . |
| APA | Ye, Changchuan , Shi, Menglei , Ren, Jingnan , Zhang, Yan , Zhang, Yeqiu , Zhang, Yingmei et al. Effects of compound probiotics on growth performance, immunity, antioxidant capacity and gut microbiota in weaned rabbits . | FRONTIERS IN VETERINARY SCIENCE , 2025 , 12 . |
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Simple Summary Iodine regulates the metabolic pathways of carbohydrates, proteins, fats, minerals, and vitamins in animals. Organic iodine overcomes the problems of low absorption and utilization rate and excessive dosage of traditional inorganic salts. Fujian yellow rabbits, a local elite variety, have a medicinal function, a high reproduction rate, and great carcass quality, presenting a huge market potential. Fujian yellow rabbits are hindgut fermenters, which are typically in a precarious balance. Gut health directly affects the health of the animals, which in turn affects production performance. This study described the effect of organic iodine in Fujian yellow rabbit diets and indicated that organic iodine improves growth performance and increases serum T3 and serum T4 concentrations. Organic iodine ameliorates gut health through adequate intestinal morphology, and active caecum fermentation, and enhances enzyme activity and intestinal immunity when adding 0.5 mg/kg organic iodine in Fujian yellow rabbit diets.Abstract Organic iodine is a new trace element additive that is highly efficient in regulating cell growth, function, and metabolism. This study demonstrated that organic iodine improves the growth performance and gut health of Fujian yellow rabbits. A total of 160 healthy rabbits of similar weight were randomly divided into four groups, which were treated with organic iodine (0, 0.5, 1.0, and 1.5 mg/kg) for 60 days. Our results indicated that organic iodine improved the growth performance, including significantly increased BW, ADG, and ADFI, and decreased F/G notably. Organic iodine improved the content of T3, T4, IgM, IgA, and IgM in serum, and intestinal mucosal immunity (IL-1 alpha, IL-2, and sIgA). Organic iodine supplementation ameliorated gut morphometry and morphology, such as higher villus height and lower crypt depth. Organic iodine increased the amount of goblet cells significantly. The 0.5 mg/kg organic iodine most increased the activities of amylase, cellulase, and trypsin in caecum. Organic iodine induced more active caecum fermentation, higher NH3-N, acetic acid, propionic acid, and butyric acid, while lowering PH. In conclusion, organic iodine improved the growth performance and gut morphometry and morphology, and increased caecum enzyme activities, active caecum fermentation, and intestinal immunity of Fujian yellow rabbits.
Keyword ：
Fujian yellow rabbits Fujian yellow rabbits growth performance growth performance gut health gut health organic iodine organic iodine
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| GB/T 7714 | Liu, Qinghua , Zhang, Yeqiu , Zhang, Jie et al. Organic Iodine Improves the Growth Performance and Gut Health of Fujian Yellow Rabbits [J]. | ANIMALS , 2024 , 14 (13) . |
| MLA | Liu, Qinghua et al. "Organic Iodine Improves the Growth Performance and Gut Health of Fujian Yellow Rabbits" . | ANIMALS 14 . 13 (2024) . |
| APA | Liu, Qinghua , Zhang, Yeqiu , Zhang, Jie , Du, Zhijian , He, Bixian , Qin, Juanqing et al. Organic Iodine Improves the Growth Performance and Gut Health of Fujian Yellow Rabbits . | ANIMALS , 2024 , 14 (13) . |
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Simple Summary Recently, the escalating prices of feedstuff resources have posed significant challenges to animal husbandry, necessitating the creation of innovative approaches to mitigate its effects. GAA (also known as N-amidinoglycine) serves as the sole precursor for creatine synthesis. GAA could enhance growth performance and regulate fat deposition to improve meat quality. Current studies on GAA mainly center on pigs and chickens, with limited reports on its effects on sheep. In our study, we used weaned Hu sheep as subjects. We aimed to explore the impact of dietary GAA supplementation on production performance, serum biochemistry, meat quality and rumen fermentation. This study provides a theoretical foundation for utilizing GAA in sheep meat production. Our findings indicate that GAA enhances growth performance, rumen fermentation and fat accumulation. In addition, GAA might enhance the quality of sheep meat, which presents a promising prospect for meat sheep breeding.Abstract Guanidinoacetic acid (GAA) can effectively improve the metabolism of energy and proteins by stimulating creatine biosynthesis. We present a study exploring the impact of GAA on production performance, serum biochemistry, meat quality and rumen fermentation in Hu sheep. A total of 144 weaned male Hu sheep (body weight 16.91 +/- 3.1 kg) were randomly assigned to four groups with three replicates of twelve sheep in each group. The diets were supplemented with 0 (CON), 500 (GAA-1), 750 (GAA-2) and 1000 mg/kg (GAA-3) of GAA (weight of feed), respectively. After a comprehensive 90-day experimental period, we discovered that the supplementation of GAA had a remarkable impact on various muscle parameters. Specifically, it significantly enhanced the average daily growth (ADG) of the animals and improved the shear force and fiber diameter of the muscle, while also reducing the drip loss and muscle fiber density. Furthermore, the addition of GAA to the feed notably elevated the serum concentrations of high-density lipoprotein cholesterol (HDL-C), total protein (TP) and globulin (GLB), as well as the enzyme activity of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px). Concurrently, there was a decrease in the levels of triglycerides (TG) and malondialdehyde (MDA) in the serum. In addition, GAA decreased the pH and the acetate-to-propionate ratio and increased the total volatile fatty acids (TVFA) and ammoniacal nitrogen (NH3-N) levels of rumen fluid. Additionally, GAA upregulated acetyl-CoA carboxylase (ACC) gene expression in the Hu sheep's muscles. In conclusion, our findings suggest that GAA supplementation not only enhances muscle quality but also positively affects serum biochemistry and ruminal metabolism, making it a potential candidate for improving the overall health and performance of Hu sheep.
Keyword ：
fatty acid metabolism fatty acid metabolism guanidinoacetic acid guanidinoacetic acid Hu sheep Hu sheep production performance production performance rumen fermentation rumen fermentation
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| GB/T 7714 | Jin, Huayun , Du, Zhijian , Fan, Xiaoyu et al. Effect of Guanidinoacetic Acid on Production Performance, Serum Biochemistry, Meat Quality and Rumen Fermentation in Hu Sheep [J]. | ANIMALS , 2024 , 14 (14) . |
| MLA | Jin, Huayun et al. "Effect of Guanidinoacetic Acid on Production Performance, Serum Biochemistry, Meat Quality and Rumen Fermentation in Hu Sheep" . | ANIMALS 14 . 14 (2024) . |
| APA | Jin, Huayun , Du, Zhijian , Fan, Xiaoyu , Qin, Liwen , Liu, Weiwei , Zhang, Yan et al. Effect of Guanidinoacetic Acid on Production Performance, Serum Biochemistry, Meat Quality and Rumen Fermentation in Hu Sheep . | ANIMALS , 2024 , 14 (14) . |
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本发明公开了一种能够改善兔肠道菌群的菌草灵芝多糖肽及其制备方法。菌草灵芝子实体切片，烘干粉碎后过筛，得到菌草灵芝粗粉；将菌草灵芝粗粉加入纯水，超声提取，超声提取完成后进行抽滤；滤液旋转蒸发浓缩，醇沉，离心，得到沉淀；将沉淀依次用无水乙醇、丙酮、无水乙醚洗涤，置于‑80℃的冰箱中冻存，完全冻住后在冷冻干燥机上冻干，得到菌草灵芝多糖肽。本发明提供的菌草灵芝多糖肽可提高兔宰前活重，还可在一定程度上改善闽西南黑兔盲肠发酵参数以及肠道菌群的结构和组成，从而改善闽西南黑兔肠道健康。
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| GB/T 7714 | 覃娟清 , 刘庆华 , 张燕 et al. 一种能够改善兔肠道菌群的菌草灵芝多糖肽及其制备方法 : CN202410228213.3[P]. | 2024-02-29 . |
| MLA | 覃娟清 et al. "一种能够改善兔肠道菌群的菌草灵芝多糖肽及其制备方法" : CN202410228213.3. | 2024-02-29 . |
| APA | 覃娟清 , 刘庆华 , 张燕 , 任静楠 , 叶长川 . 一种能够改善兔肠道菌群的菌草灵芝多糖肽及其制备方法 : CN202410228213.3. | 2024-02-29 . |
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【目的】研究日粮中添加菌草灵芝多糖肽(JCGLPP)对闽西南黑兔生长性能、血液生化指标及免疫功能的影响,为JCGLPP在肉兔中的应用提供依据。【方法】选取(33±2) d、初始体质量(655.65±25.90)g、健康状况良好的断奶闽西南黑兔公兔100只,随机分为4组,对照组饲喂基础饲粮,试验Ⅰ、Ⅱ、Ⅲ组分别饲喂在基础饲粮中添加50,100和150 mg/kg JCGLPP的日粮,56 d后统计腹泻率和死亡率,测算平均日采食量(ADFI)、平均日增重(ADG)以及料重比(F/G);屠宰后取背腰最长肌,测定pH值、滴水损失率和剪切力;采集血清,测定总蛋白(TP)、白蛋白(ALB)质量浓度,尿素氮(UN)、丙二醛(MDA)浓度,超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-Px)活性以及IgG、IgA、IgM和IL-6质量浓度;计算心脏、肝脏、肾脏、圆小囊、脾脏、胸腺和蚓突器官指数;测定十二指肠、空肠、回肠黏膜炎性因子IL-1α、IL-2和分泌型免疫球蛋白(sIgA)质量浓度及肠道淀粉酶、纤维素酶和胰蛋白酶活性。【结果】(1)各组间兔的终末体质量、平均日增重、平均采食量和料重比均无显著差异(P>0.05);对照组兔的腹泻率和死亡率最高,Ⅱ组兔的腹泻率显著低于对照(P<0.05)。(2)试验组兔肌肉的pH、滴水损失和剪切力均与对照无显著差异(P>0.05)。(3)Ⅱ组兔血液中的TP、ALB质量浓度及SOD、GSH-Px活性显著高于对照(P<0.05),而UN和MDA浓度显著低于对照(P<0.05)。(4)Ⅱ组兔血液中的IgG、IgA、IgM质量浓度均显著高于对照(P<0.05),而IL-6质量浓度各组差异不显著(P>0.05)。(5)各组兔免疫器官指数差异均不显著(P>0.05);试验组兔十二指肠、空肠、回肠IL-1α、IL-2和sIgA质量浓度大多显著高于对照(P<0.05),肠道淀粉酶活性均显著低于对照(P<0.05),Ⅰ组兔的肠道纤维素酶和胰蛋白酶活性、Ⅱ组兔的肠道胰蛋白酶活性显著高于对照(P<0.05)。【结论】JCGLPP对闽西南黑兔的促生长作用不明显,但能提高机体的抗氧化和免疫能力,降低腹泻率和死亡率,添加量以100 mg/kg为宜。
Keyword ：
免疫机能 免疫机能 生长性能 生长性能 菌草灵芝多糖肽 菌草灵芝多糖肽 血液生化指标 血液生化指标 闽西南黑兔 闽西南黑兔
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| GB/T 7714 | 覃娟清 , 杜志坚 , 张富 et al. 菌草灵芝多糖肽对闽西南黑兔生长性能、血液生化指标及免疫机能的影响 [J]. | 西北农林科技大学学报(自然科学版) , 2024 , (04) : 1-9 . |
| MLA | 覃娟清 et al. "菌草灵芝多糖肽对闽西南黑兔生长性能、血液生化指标及免疫机能的影响" . | 西北农林科技大学学报(自然科学版) 04 (2024) : 1-9 . |
| APA | 覃娟清 , 杜志坚 , 张富 , 秦莉雯 , 郭宇康 , 刘庆华 . 菌草灵芝多糖肽对闽西南黑兔生长性能、血液生化指标及免疫机能的影响 . | 西北农林科技大学学报(自然科学版) , 2024 , (04) , 1-9 . |
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The aim of this study was to investigate the effects of mixed organic acids (MOAs) on growth performance, immunity, antioxidants, intestinal digestion, and barrier function in Ira rabbits. A total of 192 weaned male Ira rabbits at 35 days of age were randomly assigned to four groups with six replicates of eight rabbits each. The rabbits in the control group (CON) were fed a basal diet, and the antibiotic group (SAL) was fed a basal diet supplemented with 60 mg/kg salinomycin. The test groups were fed a basal diet supplemented with 1000 mg/kg and 2000 mg/kg MOAs (MOA1 and MOA2, respectively). The experiment lasted for 55 days. The results showed that the ADG of Ira rabbits in the SAL group and MOA1 group was higher than that in the CON group (p < 0.05). The serum IL-6 and liver MDA levels of Ira rabbits in the SAL group, MOA1 group, and MOA2 group were lower than those in the CON group (p < 0.05). In addition, sIgA levels in the jejunal mucosa of Ira rabbits in the SAL group and MOA1 group were increased compared with those in the CON group (p < 0.05). Compared with the CON group, the gene expression of IL-6 was decreased (p < 0.05) in the jejunal mucosa of Ira rabbits in the SAL, MOA1, and MOA2 groups, while the gene expression of IL-1 beta tended to decrease (p = 0.077) and the IL-10 content tended to increase (p = 0.062). Moreover, the gene expression of ZO-1 in the jejunal mucosa of Ira rabbits was elevated in the MOA1 group compared with the CON group (p < 0.05). In conclusion, dietary supplementation with MOAs can improve growth performance, enhance immune function and antioxidant capacity, and maintain the intestinal barrier in weaned Ira rabbits.
Keyword ：
antioxidant antioxidant growth performance growth performance immunity immunity intestinal function intestinal function Ira rabbit Ira rabbit mixed organic acids mixed organic acids
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| GB/T 7714 | Lin, Zhixin , Yang, Guofeng , Zhang, Min et al. Dietary Supplementation of Mixed Organic Acids Improves Growth Performance, Immunity, and Antioxidant Capacity and Maintains the Intestinal Barrier of Ira Rabbits [J]. | ANIMALS , 2023 , 13 (19) . |
| MLA | Lin, Zhixin et al. "Dietary Supplementation of Mixed Organic Acids Improves Growth Performance, Immunity, and Antioxidant Capacity and Maintains the Intestinal Barrier of Ira Rabbits" . | ANIMALS 13 . 19 (2023) . |
| APA | Lin, Zhixin , Yang, Guofeng , Zhang, Min , Yang, Rui , Wang, Yating , Guo, Pingting et al. Dietary Supplementation of Mixed Organic Acids Improves Growth Performance, Immunity, and Antioxidant Capacity and Maintains the Intestinal Barrier of Ira Rabbits . | ANIMALS , 2023 , 13 (19) . |
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