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学者姓名：张怡
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Abstract ：
The versatile and pivotal roles of the phytohormone auxin in regulating plant growth and development are typically linked to its directional transport, relying on the polarized PIN-FORMED (PIN) auxin exporters at the plasma membrane (PM). For decades, auxin has been proposed to promote PIN polarization, generating self-regulatory feedback mediating much of plant development, but mechanistic insight into this regulation is lacking. Here, we uncover an auxin-induced protein complex at the PM, containing auxin co-receptors trans-membrane kinases (TMKs) and PIN1 auxin exporter, as the core machinery that underlies this feedback regulation. Auxin promotes PIN1 phosphorylation by TMKs, modulating PIN1 polarization and transport activity. We also provide evidence that PIN1-exported extracellular auxin is crucial for TMK activation and cell elongation, thus forming the simplest two-element self-regulatory feedback circuit. Thus, these findings offer direct mechanistic insights into a potential self-organizing circuit for auxin signaling and transport to ensure proper plant development in Arabidopsis.
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| GB/T 7714 | Huang Rongfeng , Wang Jiacheng , Chang Mingzeng et al. TMK-PIN1 drives a short self-organizing circuit for auxin export and signaling in Arabidopsis [J]. | DEVELOPMENTAL CELL , 2026 , 61 (1) . |
| MLA | Huang Rongfeng et al. "TMK-PIN1 drives a short self-organizing circuit for auxin export and signaling in Arabidopsis" . | DEVELOPMENTAL CELL 61 . 1 (2026) . |
| APA | Huang Rongfeng , Wang Jiacheng , Chang Mingzeng , Tang Wenxin , Yu Yongqiang , Zhang Yi et al. TMK-PIN1 drives a short self-organizing circuit for auxin export and signaling in Arabidopsis . | DEVELOPMENTAL CELL , 2026 , 61 (1) . |
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本发明属于免疫类生物制品技术领域，具体涉及一种缓解吡虫啉诱导免疫损伤的带鱼免疫肽FAFU‑C及其制备方法。本发明所述带鱼免疫肽FAFU‑C的氨基酸序列为Asn‑Gln‑Val‑Ala‑Met‑Asn‑Pro‑Thr‑Asn‑Thr‑Val‑Phe‑Asp‑Ala‑Lys。使用吡虫啉对小鼠进行干预，其免疫功能受到损伤，表明吡虫啉建立免疫损伤模型小鼠具有一定的可行性，而本发明本发明所述带鱼免疫肽FAFU‑C可缓解经吡虫啉诱导的小鼠免疫损伤。
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| GB/T 7714 | 胡嘉淼 , 侯若婷 , 何欣 et al. 缓解吡虫啉诱导免疫损伤的带鱼免疫肽FAFU-C及其制备方法 : CN202410327841.7[P]. | 2024-03-21 . |
| MLA | 胡嘉淼 et al. "缓解吡虫啉诱导免疫损伤的带鱼免疫肽FAFU-C及其制备方法" : CN202410327841.7. | 2024-03-21 . |
| APA | 胡嘉淼 , 侯若婷 , 何欣 , 张怡 , 林少玲 . 缓解吡虫啉诱导免疫损伤的带鱼免疫肽FAFU-C及其制备方法 : CN202410327841.7. | 2024-03-21 . |
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通过网络药理学探究姜黄素光动力技术的作用和分子机制，为进一步研究姜黄素光动力技术的分子机制提供理论指导。文章通过PharmMapper、SwissTargetPrediction、STITCH、GeneCards等在线分析平台预测姜黄素与光动力技术相关靶点，基于DAVID数据库进行GO功能注释和KEGG富集分析筛选姜黄素运用于光动力的可能机制，使用cytoscape 3.9.1软件构建蛋白—蛋白互作（PPI）网络图，获取核心靶点。结果显示：网络药理学分析可预测78个姜黄素与光动力技术共同靶点，GO富集分析的结果主要涉及RNA聚合酶Ⅱ启动子转录的正与负调控、凋亡过程的正与负调控、信号转导、对药物的反应、对外来刺激的反应、蛋白质磷酸化、炎症反应等173个相关生物过程；KEGG通路富集分析得到癌症的途径、PI3K-Akt信号通路、癌症中的蛋白聚糖、乙型肝炎、脂质与动脉粥样硬化、MAPK信号通路等90条潜在作用通路；PPI网络分析预测核心靶点包括AKT1、TNF、CASP3、STAT3、EGFR、ESR1、SRC、PTGS2、MMP9、ANXA5等。
Keyword ：
作用机制 作用机制 信号通路 信号通路 光动力技术 光动力技术 姜黄素 姜黄素 网络药理学 网络药理学
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| GB/T 7714 | 戴钰洁 , 林中景 , 尹蕊 et al. 基于网络药理学探究姜黄素光动力技术机制 [J]. | 福建轻纺 , 2025 , 8 (01) : 36-43 . |
| MLA | 戴钰洁 et al. "基于网络药理学探究姜黄素光动力技术机制" . | 福建轻纺 8 . 01 (2025) : 36-43 . |
| APA | 戴钰洁 , 林中景 , 尹蕊 , 张怡 , 林少玲 . 基于网络药理学探究姜黄素光动力技术机制 . | 福建轻纺 , 2025 , 8 (01) , 36-43 . |
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High-salt diet led to a series of health issues, the development of low-salt products has attracted the attention of the food industry. Here, W1/O/W2 emulsion was prepared for salt reduction in soy sauce. The stability of emulsion was investigated in this work, the results indicated that pasteurization and storage at 4 degrees C effectively contributed to enhancing the stability of the W1/O/W2 emulsion. Moreover, the findings of electronic nose, electronic tongue, quantitative descriptive analysis and gas chromatography-ion mobility spectrometry demonstrated that salt-reduced soy sauce maintained an excellent flavor. Compared with the control groups, the aldehydes and alcohols content in salt-reduced soy sauce increased. Notably, quantitative descriptive analysis showed that W1/O/W2 emulsion enhanced the saltiness perception of salt-reduced soy sauce, in which two saltreduced soy sauce achieved 19.36% and 19.23% salinity reduction respectively and possessed the salinity perception was similar to the control groups. Furthermore, salt-reduced soy sauce exhibited robust stability over 28 days of storage. These findings underscored the potential of double emulsion for salt-reduced soy sauce formulations and will provide new insights into salt reduction strategies. The W1/O/W2 emulsion provides theoretical basis for promoting healthy diet of consumers and improving public health.
Keyword ：
Double emulsions Double emulsions Salt reduction Salt reduction Sensory evaluation Sensory evaluation Sodium glutamate Sodium glutamate Soy sauce Soy sauce
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| GB/T 7714 | Zhang, Fan , Huang, Luyao , Zeng, Hongliang et al. Enhanced salt perception of soy sauce based on emulsion salt reduction strategy [J]. | LWT-FOOD SCIENCE AND TECHNOLOGY , 2025 , 220 . |
| MLA | Zhang, Fan et al. "Enhanced salt perception of soy sauce based on emulsion salt reduction strategy" . | LWT-FOOD SCIENCE AND TECHNOLOGY 220 (2025) . |
| APA | Zhang, Fan , Huang, Luyao , Zeng, Hongliang , Zheng, Baodong , Zhang, Yi . Enhanced salt perception of soy sauce based on emulsion salt reduction strategy . | LWT-FOOD SCIENCE AND TECHNOLOGY , 2025 , 220 . |
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BACKGROUND: Dictyophora indusiata polysaccharide is an important bioactive component of D. indusiata, playing an important role in alleviating inflammation. The present study aimed to investigate the anti-inflammatory effect and mechanism of D. indusiata polysaccharide on lipopolysaccharide (LPS)-induced intestinal inflammation in mice. RESULTS: Our results indicated that D. indusiata polysaccharide ameliorated intestinal inflammation of mice by increasing the body weight, the number of goblet cells and decreasing inflammatory cell infiltration. In addition, D. indusiata polysaccharide significantly up-regulated expression of ZO-1, Occuldin mRNA, which were 2.55-fold and 2.28-fold higher than the LPS group, respectively. In particular, D. indusiata polysaccharide effectively inhibited the Toll-like receptor 4 (TLR4)/ c-Jun NH2-terminal kinase (JNK) signalling pathway which was 0.34-fold and 0.49-fold of gene expression and 0.41-fold and 0.39-fold of protein expression in the LPS group, respectively. CONCLUSION: The results of the present study suggested that D. indusiata polysaccharide exerted anti-inflammatory and intestinal protective effects by inhibiting the TLR4/JNK signaling pathway, which will provide a basis for the potential value of D. indusiata polysaccharide as prebiotics in food applications. (c) 2024 Society of Chemical Industry.
Keyword ：
anti-inflammatory anti-inflammatory Dictyophora indusiata Dictyophora indusiata polysaccharide polysaccharide TLR4/JNK signaling pathway TLR4/JNK signaling pathway
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| GB/T 7714 | Zhang, Zihao , Zeng, Zhikun , Wang, Lin et al. Dictyophora indusiata polysaccharide attenuated LPS-induced intestinal inflammation of mice via the TLR4/JNK signaling pathway [J]. | JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE , 2025 , 105 (2) : 974-981 . |
| MLA | Zhang, Zihao et al. "Dictyophora indusiata polysaccharide attenuated LPS-induced intestinal inflammation of mice via the TLR4/JNK signaling pathway" . | JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE 105 . 2 (2025) : 974-981 . |
| APA | Zhang, Zihao , Zeng, Zhikun , Wang, Lin , Xiong, Bin , Zheng, Baodong , Zhang, Yi et al. Dictyophora indusiata polysaccharide attenuated LPS-induced intestinal inflammation of mice via the TLR4/JNK signaling pathway . | JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE , 2025 , 105 (2) , 974-981 . |
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This study aimed to investigate the chemical structure and prebiotic activity of a Dictyophora indusiata polysaccharide fraction DIP0p. Our results indicated that DIP0p belongs to a heteropolysaccharide composed of glucose, galactose, mannose and xylose, accounting for 53.25 %, 24.18 %, 19.19 % and 3.37 %, respectively. Methylation and NMR results suggested that the main glycosidic bonds of DIP0p is -*3)-Glcp-(1 -* with -*4)Glcp-(1-*, -*3,4)-Glcp-(1-*, -*3,4)-Galp-(1 -* and -*6)-Manp-(1 -* branches. In addition, DIP0p increased the abundance of benificial bacteria during the in vitro fecal fermentation, including Phascolarctobacterium, Parabacteroides and Bifidobacterium. It is remarkable that DIP0p improved the level of acetic acid, propionic acid, and butyric acid of the fermentation system, which were 1.31, 1.52, and 2.64 folds higher than the Controls, respectively. In summary, this study comprehensively analyzed the structure and probiotic activity of DIP0p, which providing a theoretical basis for the development of the functional foods.
Keyword ：
Dictyophora indusiata Dictyophora indusiata Microbiota Microbiota Polysaccharide Polysaccharide SCFAs SCFAs Structure Structure
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| GB/T 7714 | Pan, Lei , Wang, Lin , Zeng, Zhikun et al. Chemical structure and prebiotic activity of a Dictyophora indusiata polysaccharide fraction [J]. | FOOD CHEMISTRY , 2025 , 463 . |
| MLA | Pan, Lei et al. "Chemical structure and prebiotic activity of a Dictyophora indusiata polysaccharide fraction" . | FOOD CHEMISTRY 463 (2025) . |
| APA | Pan, Lei , Wang, Lin , Zeng, Zhikun , Zhang, Zihao , Zheng, Baodong , Zhang, Yi . Chemical structure and prebiotic activity of a Dictyophora indusiata polysaccharide fraction . | FOOD CHEMISTRY , 2025 , 463 . |
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This study aimed to comprehensively investigate the structure of purified exopolysaccharide EPS821-2, and the effect of Weissella cibaria FAFU821 on bread quality. Here, the findings determined that EPS821-2 was composed of 95.97 % glucose and 3.31 % mannose, with a molecular weight of 758.77 kDa. In addition, EPS821-2 was mainly composed of alpha-(1 -* 6) linkages with branches containing alpha-(1 -* 2), alpha-(1, 3 -* 6), and alpha-(1, 4 -* 6). Interestingly, EPS821-2 exhibited a three-dimensional structure, which led to the hypothesis that W. cibaria FAFU821 contributed to the quality of bread. The results revealed that W. cibaria FAFU821 enhanced the viscoelasticity of sourdough. It is remarkable that sourdough bread femented by W. cibaria FAFU821 had an excellent water holding capacity and lower hardness. In particular, W. cibaria FAFU821 increased the volatile profile of bread, including linoleic acid ethyl ester and acetic acid. This work provided the scientific insight for the applications of W. cibaria FAFU821 and its synthesized EPS821-2 in bakery innovation.
Keyword ：
Bread quality Bread quality Exopolysaccharide Exopolysaccharide Three-dimensional structure Three-dimensional structure Weissella cibaria Weissella cibaria
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| GB/T 7714 | Zhang, Fan , Wang, Xiaoying , Wang, Lin et al. Weissella cibaria FAFU821 improved bread quality based on the three-dimensional network structure of its exopolysaccharide [J]. | FOOD CHEMISTRY , 2025 , 475 . |
| MLA | Zhang, Fan et al. "Weissella cibaria FAFU821 improved bread quality based on the three-dimensional network structure of its exopolysaccharide" . | FOOD CHEMISTRY 475 (2025) . |
| APA | Zhang, Fan , Wang, Xiaoying , Wang, Lin , Zheng, Baodong , Zhang, Yi , Pan, Lei . Weissella cibaria FAFU821 improved bread quality based on the three-dimensional network structure of its exopolysaccharide . | FOOD CHEMISTRY , 2025 , 475 . |
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Laminaria japonica polysaccharide (LJP) is an important nutrient of Laminaria japonica, and the extraction rate and the bioactivity of LJP were improved with the steam explosion (SE) method according to our preliminary research. Here, the effects of steam-exploded Laminaria japonica polysaccharide (LJPS) on flavor, storage stability, and dynamic in vitro digestive properties of set yogurt were investigated in this study. The results suggested that the addition of 0.1 % LJP and LJPS maintained the taste and the odor of set yogurt. In addition, the water holding capacity was increased significantly by 1.067 and 1.066 folds with LJP and LJPS compared with the control groups, respectively. Furthermore, the water distribution was optimized with the addition of LJP and LJPS. In particular, LJP improved the adhesiveness of set yogurt by texture profile analysis. Moreover, the viability of Lactobacilli and Lactococci was sustained during the dynamic in vitro digesting process with LJP and LJPS. Overall, the study provides theoretical guidance for the application of marine plant polysaccharides in the food industry.
Keyword ：
Dynamic in vitro digestion Dynamic in vitro digestion Laminaria japonica Laminaria japonica Polysaccharide Polysaccharide Set yogurt Set yogurt Steam explosion Steam explosion
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| GB/T 7714 | Wu, Jiabin , Lin, Yaqing , Zeng, Zhikun et al. Steam-exploded Laminaria japonica polysaccharide improved set yogurt quality: Based on flavor, storage stability and dynamic in vitro digestive properties [J]. | INNOVATIVE FOOD SCIENCE & EMERGING TECHNOLOGIES , 2025 , 100 . |
| MLA | Wu, Jiabin et al. "Steam-exploded Laminaria japonica polysaccharide improved set yogurt quality: Based on flavor, storage stability and dynamic in vitro digestive properties" . | INNOVATIVE FOOD SCIENCE & EMERGING TECHNOLOGIES 100 (2025) . |
| APA | Wu, Jiabin , Lin, Yaqing , Zeng, Zhikun , Wang, Lin , Zhang, Fan , Huang, Hangyu et al. Steam-exploded Laminaria japonica polysaccharide improved set yogurt quality: Based on flavor, storage stability and dynamic in vitro digestive properties . | INNOVATIVE FOOD SCIENCE & EMERGING TECHNOLOGIES , 2025 , 100 . |
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Effective release of sodium ions from the food matrix is a major challenge in salt reduction strategies. In this study, we modified the structure and properties of NaCl-loaded emulsion gels (NEGs) to enhance its saltiness perception. We analyzed the impact of different emulsion contents and salt concentrations on the sodium ion release characteristics and salty taste perception of NEGs through in vitro oral digestion experiments combined with static-dynamic sensory evaluation. Increasing the emulsion content resulted in a higher porosity and larger pore size in the three-dimensional gel network structure of NEGs, promoting uneven distribution of sodium ions and enhancing the gel network structure. This increase also made NEGs more resilient, leading to greater mechanical disruption during oral digestion and facilitating sufficient release of sodium Na+ from NEGs, thereby enhancing its salty taste stimulation. Furthermore, there was no significant correlation between salt concentration and textural properties of NEGs; however, increasing salt concentration slightly altered the microstructure while enhancing their Na+ release capacity. This study can potentially lead to the development of lowsodium foods.
Keyword ：
Emulsion gel Emulsion gel Microstructure Microstructure Rheological properties Rheological properties Saltiness perception Saltiness perception Sodium release Sodium release
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| GB/T 7714 | Xu, Yingru , Su, Jinhan , Jiang, Shiyi et al. Preparation and saltiness characterization of NaCl-loaded O/W emulsion gel [J]. | JOURNAL OF FOOD ENGINEERING , 2025 , 399 . |
| MLA | Xu, Yingru et al. "Preparation and saltiness characterization of NaCl-loaded O/W emulsion gel" . | JOURNAL OF FOOD ENGINEERING 399 (2025) . |
| APA | Xu, Yingru , Su, Jinhan , Jiang, Shiyi , Chen, Dulian , Zhang, Yi , Zeng, Hongliang . Preparation and saltiness characterization of NaCl-loaded O/W emulsion gel . | JOURNAL OF FOOD ENGINEERING , 2025 , 399 . |
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Bile acids serve as a critical metabolic pathway for cholesterol catabolism. Accelerating hepatic conversion of cholesterol to bile acids and enhancing their fecal excretion may constitute an effective strategy for cholesterol homeostasis regulation. This study investigated the lipid-lowering mechanisms of lotus seed resistant starch (LRS) through integrated analysis of gut microbiota dynamics and bile acid metabolism. A rat model of hyperlipidemia was created and intervened with LRS. Fecal samples from various time periods were collected to study the changes in microbiota and bile acids, and the correlation network diagram was established. The findings showed that LRS inhibited the growth of Prevotella and Allobaculum, and promoted the excretion of cholic acid (CA), chenodeoxycholic acid (CDCA), alpha-muricholic acid (a-MCA), ursocholic acid (UCA) in hyperlipidemic rats. Furthermore, total cholesterol (TCHO), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C) were negatively correlated with CA, CDCA and UCA. TCHO was positively correlated with Prevotella, and high-density lipoprotein cholesterol (HDL-C) was positively correlated with a-MCA. Regulating the gut microbiota such as Prevotella and accelerating the transformation of liver cholesterol into primary bile acids (CA, CDCA) for excretion from the body was one of the effective means for LRS to ameliorate blood lipid levels in hyperlipidemic rats.
Keyword ：
Bile acids Bile acids Correlation network Correlation network Fecal flora Fecal flora Hypolipidemic effect Hypolipidemic effect Lotus seed resistant starch Lotus seed resistant starch
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| GB/T 7714 | Lei, Suzhen , Jiang, Yijun , Lin, Zhixiong et al. Lotus seed resistant starch ameliorates blood lipid by regulating flora and promoting bile acids excretion in hyperlipidemic rats [J]. | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES , 2025 , 319 . |
| MLA | Lei, Suzhen et al. "Lotus seed resistant starch ameliorates blood lipid by regulating flora and promoting bile acids excretion in hyperlipidemic rats" . | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 319 (2025) . |
| APA | Lei, Suzhen , Jiang, Yijun , Lin, Zhixiong , Zheng, Baodong , Zhang, Yi , Zeng, Hongliang . Lotus seed resistant starch ameliorates blood lipid by regulating flora and promoting bile acids excretion in hyperlipidemic rats . | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES , 2025 , 319 . |
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