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学者姓名:张怡
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The versatile and pivotal roles of the phytohormone auxin in regulating plant growth and development are typically linked to its directional transport, relying on the polarized PIN-FORMED (PIN) auxin exporters at the plasma membrane (PM). For decades, auxin has been proposed to promote PIN polarization, generating self-regulatory feedback mediating much of plant development, but mechanistic insight into this regulation is lacking. Here, we uncover an auxin-induced protein complex at the PM, containing auxin co-receptors trans-membrane kinases (TMKs) and PIN1 auxin exporter, as the core machinery that underlies this feedback regulation. Auxin promotes PIN1 phosphorylation by TMKs, modulating PIN1 polarization and transport activity. We also provide evidence that PIN1-exported extracellular auxin is crucial for TMK activation and cell elongation, thus forming the simplest two-element self-regulatory feedback circuit. Thus, these findings offer direct mechanistic insights into a potential self-organizing circuit for auxin signaling and transport to ensure proper plant development in Arabidopsis.
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| GB/T 7714 | Huang Rongfeng , Wang Jiacheng , Chang Mingzeng et al. TMK-PIN1 drives a short self-organizing circuit for auxin export and signaling in Arabidopsis [J]. | DEVELOPMENTAL CELL , 2026 , 61 (1) . |
| MLA | Huang Rongfeng et al. "TMK-PIN1 drives a short self-organizing circuit for auxin export and signaling in Arabidopsis" . | DEVELOPMENTAL CELL 61 . 1 (2026) . |
| APA | Huang Rongfeng , Wang Jiacheng , Chang Mingzeng , Tang Wenxin , Yu Yongqiang , Zhang Yi et al. TMK-PIN1 drives a short self-organizing circuit for auxin export and signaling in Arabidopsis . | DEVELOPMENTAL CELL , 2026 , 61 (1) . |
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BACKGROUND: Dictyophora indusiata polysaccharide is an important bioactive component of D. indusiata, playing an important role in alleviating inflammation. The present study aimed to investigate the anti-inflammatory effect and mechanism of D. indusiata polysaccharide on lipopolysaccharide (LPS)-induced intestinal inflammation in mice. RESULTS: Our results indicated that D. indusiata polysaccharide ameliorated intestinal inflammation of mice by increasing the body weight, the number of goblet cells and decreasing inflammatory cell infiltration. In addition, D. indusiata polysaccharide significantly up-regulated expression of ZO-1, Occuldin mRNA, which were 2.55-fold and 2.28-fold higher than the LPS group, respectively. In particular, D. indusiata polysaccharide effectively inhibited the Toll-like receptor 4 (TLR4)/ c-Jun NH2-terminal kinase (JNK) signalling pathway which was 0.34-fold and 0.49-fold of gene expression and 0.41-fold and 0.39-fold of protein expression in the LPS group, respectively. CONCLUSION: The results of the present study suggested that D. indusiata polysaccharide exerted anti-inflammatory and intestinal protective effects by inhibiting the TLR4/JNK signaling pathway, which will provide a basis for the potential value of D. indusiata polysaccharide as prebiotics in food applications. (c) 2024 Society of Chemical Industry.
Keyword :
anti-inflammatory anti-inflammatory Dictyophora indusiata Dictyophora indusiata polysaccharide polysaccharide TLR4/JNK signaling pathway TLR4/JNK signaling pathway
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| GB/T 7714 | Zhang, Zihao , Zeng, Zhikun , Wang, Lin et al. Dictyophora indusiata polysaccharide attenuated LPS-induced intestinal inflammation of mice via the TLR4/JNK signaling pathway [J]. | JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE , 2025 , 105 (2) : 974-981 . |
| MLA | Zhang, Zihao et al. "Dictyophora indusiata polysaccharide attenuated LPS-induced intestinal inflammation of mice via the TLR4/JNK signaling pathway" . | JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE 105 . 2 (2025) : 974-981 . |
| APA | Zhang, Zihao , Zeng, Zhikun , Wang, Lin , Xiong, Bin , Zheng, Baodong , Zhang, Yi et al. Dictyophora indusiata polysaccharide attenuated LPS-induced intestinal inflammation of mice via the TLR4/JNK signaling pathway . | JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE , 2025 , 105 (2) , 974-981 . |
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This study aimed to investigate the chemical structure and prebiotic activity of a Dictyophora indusiata polysaccharide fraction DIP0p. Our results indicated that DIP0p belongs to a heteropolysaccharide composed of glucose, galactose, mannose and xylose, accounting for 53.25 %, 24.18 %, 19.19 % and 3.37 %, respectively. Methylation and NMR results suggested that the main glycosidic bonds of DIP0p is -*3)-Glcp-(1 -* with -*4)Glcp-(1-*, -*3,4)-Glcp-(1-*, -*3,4)-Galp-(1 -* and -*6)-Manp-(1 -* branches. In addition, DIP0p increased the abundance of benificial bacteria during the in vitro fecal fermentation, including Phascolarctobacterium, Parabacteroides and Bifidobacterium. It is remarkable that DIP0p improved the level of acetic acid, propionic acid, and butyric acid of the fermentation system, which were 1.31, 1.52, and 2.64 folds higher than the Controls, respectively. In summary, this study comprehensively analyzed the structure and probiotic activity of DIP0p, which providing a theoretical basis for the development of the functional foods.
Keyword :
Dictyophora indusiata Dictyophora indusiata Microbiota Microbiota Polysaccharide Polysaccharide SCFAs SCFAs Structure Structure
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| GB/T 7714 | Pan, Lei , Wang, Lin , Zeng, Zhikun et al. Chemical structure and prebiotic activity of a Dictyophora indusiata polysaccharide fraction [J]. | FOOD CHEMISTRY , 2025 , 463 . |
| MLA | Pan, Lei et al. "Chemical structure and prebiotic activity of a Dictyophora indusiata polysaccharide fraction" . | FOOD CHEMISTRY 463 (2025) . |
| APA | Pan, Lei , Wang, Lin , Zeng, Zhikun , Zhang, Zihao , Zheng, Baodong , Zhang, Yi . Chemical structure and prebiotic activity of a Dictyophora indusiata polysaccharide fraction . | FOOD CHEMISTRY , 2025 , 463 . |
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This study aimed to comprehensively investigate the structure of purified exopolysaccharide EPS821-2, and the effect of Weissella cibaria FAFU821 on bread quality. Here, the findings determined that EPS821-2 was composed of 95.97 % glucose and 3.31 % mannose, with a molecular weight of 758.77 kDa. In addition, EPS821-2 was mainly composed of alpha-(1 -* 6) linkages with branches containing alpha-(1 -* 2), alpha-(1, 3 -* 6), and alpha-(1, 4 -* 6). Interestingly, EPS821-2 exhibited a three-dimensional structure, which led to the hypothesis that W. cibaria FAFU821 contributed to the quality of bread. The results revealed that W. cibaria FAFU821 enhanced the viscoelasticity of sourdough. It is remarkable that sourdough bread femented by W. cibaria FAFU821 had an excellent water holding capacity and lower hardness. In particular, W. cibaria FAFU821 increased the volatile profile of bread, including linoleic acid ethyl ester and acetic acid. This work provided the scientific insight for the applications of W. cibaria FAFU821 and its synthesized EPS821-2 in bakery innovation.
Keyword :
Bread quality Bread quality Exopolysaccharide Exopolysaccharide Three-dimensional structure Three-dimensional structure Weissella cibaria Weissella cibaria
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| GB/T 7714 | Zhang, Fan , Wang, Xiaoying , Wang, Lin et al. Weissella cibaria FAFU821 improved bread quality based on the three-dimensional network structure of its exopolysaccharide [J]. | FOOD CHEMISTRY , 2025 , 475 . |
| MLA | Zhang, Fan et al. "Weissella cibaria FAFU821 improved bread quality based on the three-dimensional network structure of its exopolysaccharide" . | FOOD CHEMISTRY 475 (2025) . |
| APA | Zhang, Fan , Wang, Xiaoying , Wang, Lin , Zheng, Baodong , Zhang, Yi , Pan, Lei . Weissella cibaria FAFU821 improved bread quality based on the three-dimensional network structure of its exopolysaccharide . | FOOD CHEMISTRY , 2025 , 475 . |
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It has been well documented that a number of polysaccharides with potent free-radical scavenging capability possess notable anti-fatigue activity. Interestingly, recent evidence also suggested mixed polysaccharides derived from multiple sources may yield augmented bioactivities compared to the polysaccharides from a single source. Therefore, in the current study, we investigated the anti-oxidant and anti-fatigue activities of a blend of polysaccharides isolated from three mushrooms. The optimal ratio of Pleurotus eryngii polysaccharide, Agrocybe aegerita polysaccharide, and Agaricus bisporus polysaccharide was firstly screened out by in vitro antioxidant assays with a Z-score comprehensive evaluation method. Then, the fatigue-reducing effects of the polysaccharide mixture at optimal ratio (1:2:2) were studied in mice. The results showed that the polysaccharide mixture exerted desirable fatigue-reducing effect evidence by significantly extended exhaustion time in the weight-loaded swimming assay (from 9.45 +/- 3.06 min to 27.65 +/- 19.84 min). Moreover, the observed fatigue-reducing effect may be attributed to its capacity to decrease fatigue-related metabolites, increase muscle glycogen reserves, and regulate energy metabolism-related transcripts in muscle tissue. Taken together, these findings highlighted the potential application of blending polysaccharides from multiple mushroom sources in mitigating fatigue.
Keyword :
Activity enhancement Activity enhancement Fatigue-reducing Fatigue-reducing Polysaccharide blend Polysaccharide blend
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| GB/T 7714 | Zheng, Peiying , Dai, Wanzhen , Lin, Xiaohui et al. Blending polysaccharides from three edible mushrooms represents a promising approach for augmenting their anti-oxidant and anti-fatigue activities [J]. | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES , 2025 , 298 . |
| MLA | Zheng, Peiying et al. "Blending polysaccharides from three edible mushrooms represents a promising approach for augmenting their anti-oxidant and anti-fatigue activities" . | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 298 (2025) . |
| APA | Zheng, Peiying , Dai, Wanzhen , Lin, Xiaohui , Lin, Shaoling , Zhang, Yi , Hu, Jiamiao . Blending polysaccharides from three edible mushrooms represents a promising approach for augmenting their anti-oxidant and anti-fatigue activities . | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES , 2025 , 298 . |
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High-salt diet led to a series of health issues, the development of low-salt products has attracted the attention of the food industry. Here, W1/O/W2 emulsion was prepared for salt reduction in soy sauce. The stability of emulsion was investigated in this work, the results indicated that pasteurization and storage at 4 degrees C effectively contributed to enhancing the stability of the W1/O/W2 emulsion. Moreover, the findings of electronic nose, electronic tongue, quantitative descriptive analysis and gas chromatography-ion mobility spectrometry demonstrated that salt-reduced soy sauce maintained an excellent flavor. Compared with the control groups, the aldehydes and alcohols content in salt-reduced soy sauce increased. Notably, quantitative descriptive analysis showed that W1/O/W2 emulsion enhanced the saltiness perception of salt-reduced soy sauce, in which two saltreduced soy sauce achieved 19.36% and 19.23% salinity reduction respectively and possessed the salinity perception was similar to the control groups. Furthermore, salt-reduced soy sauce exhibited robust stability over 28 days of storage. These findings underscored the potential of double emulsion for salt-reduced soy sauce formulations and will provide new insights into salt reduction strategies. The W1/O/W2 emulsion provides theoretical basis for promoting healthy diet of consumers and improving public health.
Keyword :
Double emulsions Double emulsions Salt reduction Salt reduction Sensory evaluation Sensory evaluation Sodium glutamate Sodium glutamate Soy sauce Soy sauce
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| GB/T 7714 | Zhang, Fan , Huang, Luyao , Zeng, Hongliang et al. Enhanced salt perception of soy sauce based on emulsion salt reduction strategy [J]. | LWT-FOOD SCIENCE AND TECHNOLOGY , 2025 , 220 . |
| MLA | Zhang, Fan et al. "Enhanced salt perception of soy sauce based on emulsion salt reduction strategy" . | LWT-FOOD SCIENCE AND TECHNOLOGY 220 (2025) . |
| APA | Zhang, Fan , Huang, Luyao , Zeng, Hongliang , Zheng, Baodong , Zhang, Yi . Enhanced salt perception of soy sauce based on emulsion salt reduction strategy . | LWT-FOOD SCIENCE AND TECHNOLOGY , 2025 , 220 . |
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Dictyophora indusiata is an edible fungus, which is known as bamboo fungus. D. indusiata polysaccharide is considered as the most important bioactive component. The aim of this study was to investigate the structure of a polysaccharide fraction from D. indusiata and the effects of D. indusiata polysaccharide on gut microbiota and metabolites in inflammatory mice. Here, the DIP1p, a polysaccharide fraction from D. indusiata, was obtained by isolation and purification using Cellulose DE-52 column and Sephadex G-200 gel column. The results showed that DIP1p is a heteropolysaccharide consisting of glucose, mannose, galactose and xylose in the ratio of 55.2 %, 28.6 %, 10.3 % and 5.9 %, which mainly linked by -*3)-Glcp-(1 -* glycosidic bonds. In addition, D. indusiata polysaccharide restored the colonic length reduction, modulated the secretion of cytokine and mitigated histological damage. It is remarkable that D. indusiata polysaccharide enhanced the abundance of beneficial bacteria Blautia and Roseburia, and increased the levels of short-chain fatty acids including acetic acid and propionic acid. Our findings indicated that D. indusiata polysaccharide remodeled gut microbiota and enhanced short-chain fatty acids levels to alleviate the inflammation.
Keyword :
Dictyophora indusiata polysaccharide Dictyophora indusiata polysaccharide Gut microbiota Gut microbiota Inflammation Inflammation Short-chain fatty acids Short-chain fatty acids Structure Structure
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| GB/T 7714 | Wang, Lin , Zhang, Zihao , Zeng, Zhikun et al. Structural characterization of polysaccharide from an edible fungus Dictyophora indusiata and the remodel function of gut microbiota in inflammatory mice [J]. | CARBOHYDRATE POLYMERS , 2025 , 351 . |
| MLA | Wang, Lin et al. "Structural characterization of polysaccharide from an edible fungus Dictyophora indusiata and the remodel function of gut microbiota in inflammatory mice" . | CARBOHYDRATE POLYMERS 351 (2025) . |
| APA | Wang, Lin , Zhang, Zihao , Zeng, Zhikun , Lin, Yaqing , Xiong, Bin , Zheng, Baodong et al. Structural characterization of polysaccharide from an edible fungus Dictyophora indusiata and the remodel function of gut microbiota in inflammatory mice . | CARBOHYDRATE POLYMERS , 2025 , 351 . |
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Type 3 resistant starch (RS3) regulates diet-related metabolic diseases by promoting intestinal short-chain fatty acids (SCFAs) and lactate production, and facilitating microbial lactate-to-butyrate fermentation. However, its precise in vivo mechanism remains unclear. Therefore, we studied the effects of type 3 lotus seed resistant starch (LRS3) and sodium lactate (SL) on colonic microbiota composition, metabolism, and lipid parameters. This study aimed to elucidate the mechanism by which LRS3 and SL modulate colonic microbiota and metabolism to mitigate hyperlipidemia in rats induced by a high-fat diet. Results showed LRS3 increased colonic microbial diversity, shifting the composition towards that of healthy rats. LRS3 intake reduced lactic acid-producing bacteria such as Allobaculum, Collinsella, and Blautia in the colon while promoting SCFAs-producing Ruminococcaceae. SL alone stimulated Lachnospiraceae growth. When both were administered, there was a significant increase in Treponema and Ruminococcaceae. The co-intervention of LRS3 and SL significantly affected lipid metabolism-related metabolites, up-regulating palmitic acid while down-regulating androsterone and phosphatidylcholine (PC) substances PC (14:0/20:4(8Z,11Z,14Z,17Z)), influencing unsaturated fatty acid biosynthesis pathways and inhibiting steroid hormone biosynthesis. Finally, via the microbial-metabolism-lipid correlation network, we identified that LRS3 and SL increased SCFAs production through Treponema and Ruminococcaceae metabolism, influencing organic acid and lipid composition in the colon. This indirectly reduced blood lipid levels in hyperlipidemic rats by modulating intestinal microecology.
Keyword :
Colonic microflora Colonic microflora Hyperlipidemic rats Hyperlipidemic rats LC-MS untargeted metabolomics LC-MS untargeted metabolomics Lotus seed resistant starch Lotus seed resistant starch Sodium lactate Sodium lactate
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| GB/T 7714 | Liu, Lu , Lei, Suzhen , Lin, Xiaoli et al. Synergistic regulation of colon microflora and metabolic environment by resistant starch and sodium lactate in hyperlipidemic rats☆ [J]. | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES , 2025 , 307 . |
| MLA | Liu, Lu et al. "Synergistic regulation of colon microflora and metabolic environment by resistant starch and sodium lactate in hyperlipidemic rats☆" . | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 307 (2025) . |
| APA | Liu, Lu , Lei, Suzhen , Lin, Xiaoli , Bodjrenou, David Mahoudjro , Zhang, Yi , Zheng, Baodong et al. Synergistic regulation of colon microflora and metabolic environment by resistant starch and sodium lactate in hyperlipidemic rats☆ . | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES , 2025 , 307 . |
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Due to the gel properties produced by the interaction of Nemipterus virgatus myofibrillar protein (NMP), abalone myofibrillar proteins (AMP) and acetylated tapioca starch (ATS), abalone fish ball has excellent textural and nutritional quality. On this basis, the interaction mechanisms of three composite gels (NMP-ATS, AMP-ATS and NMP-AMP-ATS) were studied from the macro- and micro-perspectives. From a macro-perspective, NMP-AMPATS had the highest gel strength (1450.92 g*mm) and G' value, and the lowest tan delta. Its dense gel network was the most uniform and compact from the SEM, and inhibited migration of immobilized water to free water. From a micro-perspective, compared with NMP-ATS and AMP-ATS of protein structure, a-helix structure of NMP-AMPATS was reduced by 21.70% and 26.35%, the /3-sheet increased by 42.57% and 18.62%, and the /3-turn increased by 11.32% and 7.26%, while the random coil remained unchanged. Fluorescence spectroscopy of NMP-AMP-ATS indicated that NMP and AMP increased partial protein unfolding and cross-linking hydrophobic interactions. Compared with the binary gel, NMP-AMP-ATS had a lower total sulfhydryl content (T-SH), enhanced hydrophobic interactions and disulfide bonds formation, which increased protein aggregation, cross-linking and gel strength. The correlation results showed that gel strength was positively correlated with /3-sheet and disulfide bond content and negatively correlated with hydrogen bonds, indicating that adding AMP reduced the T-SH of the gel network, which was interconnected by disulfide bonds. Heating weakened hydrogen bond interactions, promoted the transformation of a-helix to /3-sheet and improved gel strength. These findings provided a theoretical basis for the future development of abalone-based surimi products.
Keyword :
Abalone Abalone Composite gels Composite gels Interaction mechanism Interaction mechanism Myofibrillar proteins Myofibrillar proteins
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| GB/T 7714 | You, Shuyi , Li, Lanxin , Wang, Yanbo et al. Interaction mechanism of composite gels of abalone myofibrillar protein, Nemipterus virgatus myofibrillar protein and acetylated tapioca starch [J]. | LWT-FOOD SCIENCE AND TECHNOLOGY , 2025 , 217 . |
| MLA | You, Shuyi et al. "Interaction mechanism of composite gels of abalone myofibrillar protein, Nemipterus virgatus myofibrillar protein and acetylated tapioca starch" . | LWT-FOOD SCIENCE AND TECHNOLOGY 217 (2025) . |
| APA | You, Shuyi , Li, Lanxin , Wang, Yanbo , Zheng, Baodong , Zhang, Yi , Zeng, Hongliang . Interaction mechanism of composite gels of abalone myofibrillar protein, Nemipterus virgatus myofibrillar protein and acetylated tapioca starch . | LWT-FOOD SCIENCE AND TECHNOLOGY , 2025 , 217 . |
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In this study, the effects of Porphyra haitanensis polysaccharides (PHP) (0.4 %, 0.8 % and 1.2 %) on the short-term retrogradation and simulated digestion in vitro properties of starches with corn starch (CS), potato starch (PS) and lotus seed starch (LS) and their potential mechanism of PHP were constructed. 0.4 % and 0.8 % PHP promoted the formation of ordered structures in PS, and all PHP suppressed short-range ordered structure rearrangements in CS and LS. PHP promoted PS-PHP complex while retarding water migration of CS-PHP and LSPHP complex. XRD showed that all PHP inhibited the short-term retrogradation of CS and LS while facilitating PS. Finally, compared to native starch, CS-0.4%PHP, CS-0.8%PHP, LS-0.8%PHP and LS-1.2%PHP had higher hydrolysis rate, but PHP could decrease that of PS. All of PHP were decreased the RS proportion of CS and LS, especially CS-0.8%PHP, LS-0.8%PHP and LS-1.2%PHP. While PHP were increased that of PS. These results will provide a scientific basis for the development of starch-based foods.
Keyword :
Porphyra haitanensis polysaccharides Porphyra haitanensis polysaccharides Short-term retrograde Short-term retrograde Starch of different crystalline forms Starch of different crystalline forms
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| GB/T 7714 | Wang, Zhiyun , Luo, Qi , Bodjrenou, David Mahoudjro et al. Effects of Porphyra haitanensis polysaccharides on the short-term retrogradation and simulated digestion in vitro of three crystalline starches [J]. | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES , 2025 , 309 . |
| MLA | Wang, Zhiyun et al. "Effects of Porphyra haitanensis polysaccharides on the short-term retrogradation and simulated digestion in vitro of three crystalline starches" . | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 309 (2025) . |
| APA | Wang, Zhiyun , Luo, Qi , Bodjrenou, David Mahoudjro , Zhang, Yi , Wang, Yanbo , Zheng, Baodong et al. Effects of Porphyra haitanensis polysaccharides on the short-term retrogradation and simulated digestion in vitro of three crystalline starches . | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES , 2025 , 309 . |
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