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学者姓名：陈炳智
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Abstract ：
Probiotics exert a favorable regulatory effect on human intestinal health. However, probiotics face challenges in overcoming the highly acidic environment of the stomach and effectively reaching the intestine, which limit their beneficial effects and bioavailability. We developed a pH-responsive probiotic embedding gel carrier, where the internal Tremella polysaccharide (TMP) and Ca2+ were cross-linked to create a porous and isolated water microenvironment for probiotics. The introduction of sodium alginate and TMP not only enhanced the mechanical properties of the gel but also contributed to the formation of an outer layer structure with pH response. The gel system had good gel properties, could be shaped freely, and protected Lactobacillus rhamnosus from stomach acid and bile salts. The in vitro simulation experiments demonstrated that the release rate of carrierprotected probiotics was found to be less than 1.99% in simulated gastric fluid, whereas nearly complete release occurred in simulated intestinal fluid, with a release rate over 95%. The survival rate of probiotics in simulated gastric and intestinal fluids could be enhanced by hydrogel carriers. Simultaneously, the carrier could enhance the resistance of probiotics to bile and antibiotic. The results showed that Alg-Ca2+-4 parts per thousand TMP gel carrier was an ideal material for probiotic delivery.
Keyword ：
Gel carrier Gel carrier Probiotic protection Probiotic protection Release Release Tremella polysaccharides Tremella polysaccharides
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| GB/T 7714 | Chu, Lulu , Deng, Youjin , Zhang, Min et al. The characteristics of sodium alginate-tremella polysaccharide assembled hydrogel induced by calcium ion and its protective effect on Lactobacillus rhamnosus [J]. | FOOD HYDROCOLLOIDS , 2025 , 160 . |
| MLA | Chu, Lulu et al. "The characteristics of sodium alginate-tremella polysaccharide assembled hydrogel induced by calcium ion and its protective effect on Lactobacillus rhamnosus" . | FOOD HYDROCOLLOIDS 160 (2025) . |
| APA | Chu, Lulu , Deng, Youjin , Zhang, Min , Chen, Jieting , Lian, Yiyang , Chen, Bingzhi et al. The characteristics of sodium alginate-tremella polysaccharide assembled hydrogel induced by calcium ion and its protective effect on Lactobacillus rhamnosus . | FOOD HYDROCOLLOIDS , 2025 , 160 . |
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为改善鲜切芋艿贮藏期间的感官品质，以永定‘六月红’芋艿为试材，探究不同贮藏温度对L-抗坏血酸(L-ascorbic acid, AA)联合超声(ultrasound, US)处理鲜切芋艿品质及货架期的影响。采用质量分数2%的AA溶液浸泡试材15 min后，进行US处理，分析贮藏期间4个不同贮藏温度(4、9、15、25℃)对处理鲜切芋艿品质的影响，并据此建立鲜切芋艿的货架期预测模型。结果表明：经AA联合US处理的鲜切芋艿在4℃低温下能明显延缓品质劣变，主要体现在抑制褐变度和失重率增加，减缓硬度和pH值下降，保持细胞膜完整性和较高的感官评分，延长贮藏期等方面。通过动力学模型结合Arrhenius方程对芋艿货架期进行预测，其实测值与预测值之间的相对误差均在±10%以内，所建模型可有效预测鲜切芋艿在4～25℃温度范围内的货架期。综上，经AA联合US处理后的鲜切芋艿最佳贮藏温度为4℃,其在该条件下的货架期为20 d,研究结果为鲜切芋艿的贮藏保鲜和销售提供了参考。
Keyword ：
L-抗坏血酸 L-抗坏血酸 ‘六月红’芋艿 ‘六月红’芋艿 货架期预测模型 货架期预测模型 贮藏品质 贮藏品质 超声 超声
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| GB/T 7714 | 陈琳 , 连伊阳 , 陈琳琳 et al. 不同贮藏温度下鲜切芋艿的品质变化及其货架期预测模型 [J]. | 陕西师范大学学报(自然科学版) , 2025 , 53 (03) : 21-31 . |
| MLA | 陈琳 et al. "不同贮藏温度下鲜切芋艿的品质变化及其货架期预测模型" . | 陕西师范大学学报(自然科学版) 53 . 03 (2025) : 21-31 . |
| APA | 陈琳 , 连伊阳 , 陈琳琳 , 章敏 , 朱志远 , 陈炳智 et al. 不同贮藏温度下鲜切芋艿的品质变化及其货架期预测模型 . | 陕西师范大学学报(自然科学版) , 2025 , 53 (03) , 21-31 . |
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Browning is the primary factor influencing the storage quality of Lyophyllum decastes fruiting bodies. Prior research has demonstrated that US treatment can enhance the storage quality of L. decastes by modulating amino acid consumption, redox balance, and energy metabolism post-harvest. This study identified differentially expressed genes across various storage periods of L. decastes using transcriptomics combined with WGCNA analysis. Sixteen core differentially expressed genes were identified, primarily enriched in pathways related to pyruvate metabolism and amino acid metabolism. qRT-PCR verification revealed an upward trend in the expression levels of LdPK genes associated with pyruvate metabolism, whereas genes such as LdPC, LdLYS21, LdDLAT, and LdlldD exhibited a downward trend. Similarly, genes involved in amino acid metabolism, including LdTRPD, LdOAT, LdIDO1/3, LdPRODH, LdMCC, and LdEGT2.2, also showed a downward trend. These findings indicate that US treatment influences key enzymes of pyruvate metabolism in postharvest L. decastes, sustains energy homeostasis, reduces amino acid consumption rates, and consequently delays postharvest quality deterioration of L. decastes.
Keyword ：
Amino acid Amino acid Lyophyllum decastes Lyophyllum decastes Pyruvate Pyruvate Transcriptomics Transcriptomics WGCNA WGCNA
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| GB/T 7714 | Chen, Bingzhi , Hu, Yuxin , Xu, Shumin et al. Ultrasound treatment inhibits postharvest browning of Lyophyllum decastes by regulating pyruvate metabolism and amino acid homeostasis: A transcriptomic and network analysis [J]. | SCIENTIA HORTICULTURAE , 2025 , 349 . |
| MLA | Chen, Bingzhi et al. "Ultrasound treatment inhibits postharvest browning of Lyophyllum decastes by regulating pyruvate metabolism and amino acid homeostasis: A transcriptomic and network analysis" . | SCIENTIA HORTICULTURAE 349 (2025) . |
| APA | Chen, Bingzhi , Hu, Yuxin , Xu, Shumin , Li, Fan , Chen, Lili , Wu, Huihua et al. Ultrasound treatment inhibits postharvest browning of Lyophyllum decastes by regulating pyruvate metabolism and amino acid homeostasis: A transcriptomic and network analysis . | SCIENTIA HORTICULTURAE , 2025 , 349 . |
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This study investigated the protective effects of carboxymethyl chitosan-dialdehyde glucan/polydopamine carrier-delivered Bacillus subtilis (PBS) on Salmonella-induced intestinal inflammation in mice. The results indicated that PBS significantly lowered the organ index and inflammatory factor levels while increasing the levels of oxidase in mice. Interestingly, after PBS intervention, the mRNA expression levels of mucin, tight junction proteins, immune proteins, and transcription factors that constitute the intestinal barrier in mice exhibited a significant increase compared to those in the model group. The intestinal flora results showed that PBS improved the abundance of Ruminococcus, Bacillus, and Roseburia, simultaneously increasing the content of short-chain fatty acids. Furthermore, the downstream protein expression of pathway genes confirmed that PBS inhibited the inflammatory response by regulating the TLR4-NF-kappa B-NLRP3 inflammasome signaling pathway. These results indicate that carrier protection for Bacillus subtilis can enhance its relief effect on mice infected with Salmonella.
Keyword ：
Anti-inflammatory Anti-inflammatory Carrier-protected Bacillus subtilis Carrier-protected Bacillus subtilis Colitis Colitis Intestinal microorganisms Intestinal microorganisms Salmonella infection Salmonella infection
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| GB/T 7714 | Chu, Lulu , Wang, Wenjie , Xie, Luyu et al. Protective effects of carboxymethyl chitosan-dialdehyde glucan/ polydopamine carrier-delivered Bacillus subtilis on the intestinal tract of mice infected with Salmonella [J]. | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES , 2025 , 310 . |
| MLA | Chu, Lulu et al. "Protective effects of carboxymethyl chitosan-dialdehyde glucan/ polydopamine carrier-delivered Bacillus subtilis on the intestinal tract of mice infected with Salmonella" . | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 310 (2025) . |
| APA | Chu, Lulu , Wang, Wenjie , Xie, Luyu , Chen, Bingzhi , Lian, Yiyang , Jiang, Yuji . Protective effects of carboxymethyl chitosan-dialdehyde glucan/ polydopamine carrier-delivered Bacillus subtilis on the intestinal tract of mice infected with Salmonella . | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES , 2025 , 310 . |
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Fresh-cut taro, renowned for its high nutritional value and convenience, is prone to rapid browning post-cutting, which hinders its storage life. This study focused on the effects of L-ascorbic acid (AA) combined with ultrasound (US) treatment (AS) on the storage quality and transcriptome analysis of fresh-cut slices of Yongding June Red Taro. Compared to the control (CK) group, AS treatment effectively reduced the weight loss rate of taro slices, maintained higher hardness, delayed the increase of browning, and inhibited the accumulation of O-2(-) and H2O2. Furthermore, the AS group showed increased glutathione levels and maintained higher activities of ascorbate peroxidase and glutathione reductase, yet decreased the contents of flavonoids and reducing sugars. Simultaneously, in the AS group, the activities of tyrosinase and lipoxygenase were lowered, thereby preserving the high sensory quality of fresh-cut taro slices. Transcriptome analysis revealed that differentially expressed genes (DEGs) between the AS and CK groups were annotated and categorized into 50 and 20 functional groups based on the Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) databases, respectively. Notably, both groups exhibited significant enrichment in processes related to photosynthesis, protein processing in the endoplasmic reticulum, and isoflavone biosynthesis. Therefore, we concluded that AS treatment could alleviate oxidative stress and maintain storage quality by regulating metabolic pathways. These findings provide insights into the physiological changes occurring in taro immediately after cutting and serve as an essential basis for developing effective storage and preservation techniques.
Keyword ：
Fresh-cut taro Fresh-cut taro L-ascorbic acid L-ascorbic acid Storage quality Storage quality Transcriptome analysis Transcriptome analysis Ultrasonic treatment Ultrasonic treatment
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| GB/T 7714 | Chen, Lin , Chen, Bingzhi , Chu, Lulu et al. The storage quality and transcriptome analysis of fresh-cut taro by L-ascorbic acid combined with ultrasonic treatment [J]. | ULTRASONICS SONOCHEMISTRY , 2025 , 112 . |
| MLA | Chen, Lin et al. "The storage quality and transcriptome analysis of fresh-cut taro by L-ascorbic acid combined with ultrasonic treatment" . | ULTRASONICS SONOCHEMISTRY 112 (2025) . |
| APA | Chen, Lin , Chen, Bingzhi , Chu, Lulu , Chen, Lili , Xie, Luyu , Deng, Youjin et al. The storage quality and transcriptome analysis of fresh-cut taro by L-ascorbic acid combined with ultrasonic treatment . | ULTRASONICS SONOCHEMISTRY , 2025 , 112 . |
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This study investigated the structure-activity relationships between SePEPs (selenium-enriched peptides) and PEPs (selenium-free peptides) and compared the antioxidant activities of SePEPs and PEPs. The results showed that SePEPs exhibited higher antioxidant activity than PEPs at the same molecular weight, with the molecular weights of 0-3500 Da exhibiting the highest in vitro antioxidant activity. Chelation between selenium and peptides led to a more compact structure and increased particle density in SePEPs. A spectroscopic analysis revealed new peaks and redshifts in SePEPs, along with a higher content of hydrophobic amino acids than PEPs. A molecular interaction modeling analysis indicated that hydrogen bonding and hydrophobic interactions primarily drove the binding between selenium-containing peptides and 1,1-diphenyl-2-picrylhydrazyl (DPPH). Moreover, the solid-phase synthesized MSePGP exhibited significantly greater antioxidant activity than glutathione at high concentrations. At 10 mg/mL, the DPPH radical scavenging rate of MSePGP was 68.5 +/- 2.2%. These findings provide a theoretical basis for the design and synthesis of selenium-enriched peptides with enhanced antioxidant properties.
Keyword ：
antioxidant activity antioxidant activity molecular interaction modeling molecular interaction modeling SePEP SePEP structural identification structural identification
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| GB/T 7714 | Chen, Lili , Nie, Menghan , Yang, Jing et al. Structural Identification and Molecular Interaction Modeling Analysis of Antioxidant Activity Selenium-Enriched Peptides from Selenium-Enriched Pleurotus eryngii [J]. | ANTIOXIDANTS , 2025 , 14 (5) . |
| MLA | Chen, Lili et al. "Structural Identification and Molecular Interaction Modeling Analysis of Antioxidant Activity Selenium-Enriched Peptides from Selenium-Enriched Pleurotus eryngii" . | ANTIOXIDANTS 14 . 5 (2025) . |
| APA | Chen, Lili , Nie, Menghan , Yang, Jing , Zhang, Weibin , Hsiang, Tom , Jiang, Yuji et al. Structural Identification and Molecular Interaction Modeling Analysis of Antioxidant Activity Selenium-Enriched Peptides from Selenium-Enriched Pleurotus eryngii . | ANTIOXIDANTS , 2025 , 14 (5) . |
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This study investigated the hepatoprotective mechanisms of Volvariella volvacea fruiting body polypeptide (VVFP, 1-3 kDa) against acute alcohol-induced liver injury using multi-omics approaches. Male ICR mice pretreated with VVFP (100-400 mg/kg) showed significantly prolonged alcohol tolerance latency (p < 0.05) and accelerated sobriety recovery compared to controls. Integrated transcriptomics and metabolomics revealed VVFP's dual regulatory effects: (1) transcriptional regulation of 36 endoplasmic reticulum stress genes (e.g., ERP57, Derl) through protein processing pathways (KEGG:04141), and (2) metabolic modulation of 23 hepatic metabolites, particularly phosphatidylcholines and organic acids, via amino acid biosynthesis and glycerophospholipid metabolism. Cross-omics analysis identified eight coregulated genes (Got1, Arg2, Srm, etc.) interacting with key metabolites (4-guanidinobutyric acid, GABA) through linoleic acid metabolism. These findings demonstrate VVFP's therapeutic potential as a functional food ingredient by highlighting its ability to simultaneously target hepatic stress responses and metabolic homeostasis during alcohol detoxification.
Keyword ：
acute alcoholic hepatitis acute alcoholic hepatitis hepatoprotective mechanisms hepatoprotective mechanisms joint analysis joint analysis metabonomics metabonomics straw mushroom straw mushroom transcriptomics transcriptomics
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| GB/T 7714 | Chen, Bingzhi , Chen, Juanqin , Wu, Huihua et al. Volvariella volvacea Polypeptide Mitigates Alcohol-Induced Liver Injury: A Multi-Omics Study [J]. | FOODS , 2025 , 14 (9) . |
| MLA | Chen, Bingzhi et al. "Volvariella volvacea Polypeptide Mitigates Alcohol-Induced Liver Injury: A Multi-Omics Study" . | FOODS 14 . 9 (2025) . |
| APA | Chen, Bingzhi , Chen, Juanqin , Wu, Huihua , Zhang, Fangyi , Chen, Lili , Zhang, Weibin et al. Volvariella volvacea Polypeptide Mitigates Alcohol-Induced Liver Injury: A Multi-Omics Study . | FOODS , 2025 , 14 (9) . |
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硒是人体必需的微量元素之一，可以通过硒蛋白或硒肽在人体内发挥生理功能。本研究以富硒刺芹侧耳子实体为原料，采用碱提酸沉法获得硒蛋白，进而通过单因素试验，筛选出最优的酶解条件，并在此基础上，进一步使用Box-Behnken设计试验组合，优化硒肽的提取工艺。再从1,1-二苯基-2-三硝基苯肼(1,1-diphenyl-2-picrylhydrazyl,DPPH)自由基、2,2'-连氮-双(3-乙基苯并噻唑-6-磺酸)[2,2'-azinobis(3-ethylbenzthiazoline-6-sulphonicacid),ABTS]自由基、羟自由基(·OH)及铁还原/抗氧化能力(ferricionreducingantioxidantpower,FRAP)这4个指标，将其与普通多肽进行比较分析。结果表明：当酶添加量8 000 U/g，酶解温度60℃，酶解时间73 min，在此工艺条件下提取的硒肽硒含量达226.33 mg/mL。富硒刺芹侧耳子实体硒肽在DPPH自由基清除率、ABTS自由基清除率、羟自由基清除率及FRAP总抗氧化能力均优于普通多肽的抗氧化特性，推测是由于硒含量与多肽具有协同增效作用，从而增强硒肽的抗氧化活性。研究结果为富硒刺芹侧耳子实体硒肽的制备及应用提供依据。
Keyword ：
刺芹侧耳 刺芹侧耳 抗氧化活性 抗氧化活性 硒含量 硒含量 硒肽 硒肽
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| GB/T 7714 | 陈莉莉 , 吴惠华 , 徐舒敏 et al. 富硒刺芹侧耳硒肽的提取工艺及其抗氧化活性 [J]. | 菌物学报 , 2025 , 44 (03) : 127-139 . |
| MLA | 陈莉莉 et al. "富硒刺芹侧耳硒肽的提取工艺及其抗氧化活性" . | 菌物学报 44 . 03 (2025) : 127-139 . |
| APA | 陈莉莉 , 吴惠华 , 徐舒敏 , 朱志远 , 谢宝贵 , 陈炳智 . 富硒刺芹侧耳硒肽的提取工艺及其抗氧化活性 . | 菌物学报 , 2025 , 44 (03) , 127-139 . |
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本发明提供了一种浅色且高产的杏鲍菇菌株，属于农业微生物领域。本发明的杏鲍菇菌株为刺芹侧耳（Pleurotus eryngii）福杏鲍64，已于2024年11月7日保藏于中国典型培养物保藏中心，保藏编号为CCTCC NO：M 20242460，保藏地址为湖北省武汉市武昌区八一路299号。‘福杏鲍64’菌盖凹面型、浅灰色，菌柄颜色洁白，有很好的开发应用前景。
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| GB/T 7714 | 刘新锐 , 陈炳智 , 邓优锦 et al. 一种浅色且高产的杏鲍菇菌株 : CN202411648008.9[P]. | 2024-11-18 . |
| MLA | 刘新锐 et al. "一种浅色且高产的杏鲍菇菌株" : CN202411648008.9. | 2024-11-18 . |
| APA | 刘新锐 , 陈炳智 , 邓优锦 , 刘芳 , 傅俊生 , 江玉姬 et al. 一种浅色且高产的杏鲍菇菌株 : CN202411648008.9. | 2024-11-18 . |
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为探究L-抗坏血酸（L-ascorbic acid,AA）联合超声（ultrasound,US）(AS)处理对鲜切芋艿片贮藏品质的影响，本实验以永定六月红芋为材料，采用质量分数为2%的AA溶液浸泡15 min后，进行US(53 kHz、400 W、10 min)处理，测定贮藏期间鲜切芋艿感官品质及褐变相关酶等指标。结果表明：与对照组相比，AS处理可以降低鲜切芋艿的失水率，维持较高的硬度，延缓褐变指数升高，降低细胞膜通透性，抑制丙二醛含量累积，抑制表面微生物繁殖，从而维持鲜切芋艿较高的感官品质；与对照组相比，贮藏期间AS处理组还能维持较高的过氧化氢酶、超氧化物歧化酶活性，降低过氧化物酶、多酚氧化酶和苯丙氨酸解氨酶活性，抑制酚类物质消耗速率，并减缓淀粉、可溶性蛋白、可溶性固形物等营养物质的流失速率，抑制可溶性醌的积累，延缓风味劣变。上述结果表明，AS处理能够保持鲜切芋艿较好的贮藏品质。
Keyword ：
L-抗坏血酸 L-抗坏血酸 褐变 褐变 贮藏品质 贮藏品质 超声处理 超声处理 鲜切芋艿 鲜切芋艿
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| GB/T 7714 | 陈琳 , 胡兴成 , 罗紫玮 et al. L-抗坏血酸联合超声处理对鲜切芋艿贮藏品质的影响 [J]. | 食品科学 , 2024 , 45 (11) : 267-277 . |
| MLA | 陈琳 et al. "L-抗坏血酸联合超声处理对鲜切芋艿贮藏品质的影响" . | 食品科学 45 . 11 (2024) : 267-277 . |
| APA | 陈琳 , 胡兴成 , 罗紫玮 , 王冕 , 涂晓媛 , 陈炳智 et al. L-抗坏血酸联合超声处理对鲜切芋艿贮藏品质的影响 . | 食品科学 , 2024 , 45 (11) , 267-277 . |
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