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学者姓名：林冬梅
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Abstract ：
Agrocybe cylindracea is an important mushroom highly valued as a functional food for its nutritional and medicinal benefits. Many bioactive extracts from A. cylindracea have been found to exhibit antitumor and antioxidant activities. This research investigated the distinct substrates that affected the physicochemical and biocomponent properties and biological efficiency of A. cylindracea. The substrates used were 48% giant juncao grass mixed with 30% Dicranopteris dichotoma grasses, 48% wasted tea leaves mixed with 30% sawdust, and 78% cottonseed hulls, all supplemented with 20% wheat bran and 2% lime. The findings indicated that A. cylindracea grown in the cotton seed hulls had a significant biological efficiency, at 35.8%, followed by the GD + DD (31.5%) and WTL + SD (28.7%). The ash content peaked in the fruiting bodies grown on giant juncao grass and D. dichotoma, while the fat content was highest in those grown on giant juncao grass and D. dichotoma, followed by wasted tea leaves and sawdust. The protein content was significantly higher in the fruiting bodies cultivated on wasted tea leaves and sawdust, followed by cottonseed hulls. The carbon dioxide emissions varied across substrates, with the highest emissions observed during the maturity stage of the fruiting bodies grown on giant juncao grass with D. dichotoma and wasted tea leaves and sawdust. Emissions decreased sharply 110 days after cultivation. Essential metabolites, such as dopamine and caffeine, were enriched in the fruiting bodies grown on wasted tea leaves, sawdust, and cottonseed hulls. In contrast, tyramine and uracil were enriched in those grown on cottonseed hulls.
Keyword ：
Agrocybe cylindracea Agrocybe cylindracea biological efficiency substrate biological efficiency substrate physicochemical properties physicochemical properties
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| GB/T 7714 | Mediatrice, Hatungimana , Aimable, Nsanzinshuti , Claude, Irambona et al. The Influence of the Divergent Substrate on Physicochemical Properties and Metabolite Profiling of Agrocybe cylindracea Cultivation [J]. | JOURNAL OF FUNGI , 2025 , 11 (2) . |
| MLA | Mediatrice, Hatungimana et al. "The Influence of the Divergent Substrate on Physicochemical Properties and Metabolite Profiling of Agrocybe cylindracea Cultivation" . | JOURNAL OF FUNGI 11 . 2 (2025) . |
| APA | Mediatrice, Hatungimana , Aimable, Nsanzinshuti , Claude, Irambona , Fallah, Nyummah , Abdelkader, Menna-Allah E. , Biregeya, Jules et al. The Influence of the Divergent Substrate on Physicochemical Properties and Metabolite Profiling of Agrocybe cylindracea Cultivation . | JOURNAL OF FUNGI , 2025 , 11 (2) . |
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Gastric ulcer (GU) is a prevalent gastrointestinal disorder that significantly impacts patients' quality of life. Current treatments, including proton pump inhibitors and H2 receptor antagonists, often present limitations such as adverse side effects and incomplete healing, highlighting the urgent need for new therapeutic agents. Ganoderma lucidum polysaccharide peptides (GL-PP) have gained attention for their potential gastroprotective properties. Notably, we characterized a novel GL-PP named GL-PPQ3, assessing its efficacy in alleviating GUs using an ethanol-induced GU mouse. Our findings indicated that GL-PPQ3 is a hyperbranched galactoglucan with a molecular weight of 41.08 kDa, predominantly composed of glucose and galactose. Comprehensive analysis, including methylation and one-dimensional and two-dimensional nuclear magnetic resonance (NMR), elucidated its structural composition, revealing the presence of 1,6-alpha-D-Galp, 1,2,6-alpha-D-Galp, 1,6-(3-D-Glcp, 1,3,6-(3-D-Glcp, and 1,4-(3-D-Glcp residues. X-ray diffraction (XRD) confirmed a predominantly amorphous structure and scanning electron microscopy (SEM) displayed aggregated spherical formations. Mechanistically, GL-PPQ3 exhibited its Gastroprotective effects through the regulation of the FAK-mediated MAPK signaling pathway. This study underscores the therapeutic potential of GL-PPQ3 as a promising candidate for GU treatment, paving the way for developing novel functional agents derived from natural sources.
Keyword ：
Apoptosis Apoptosis Focal adhesion kinase Focal adhesion kinase Ganoderma lucidum polysaccharide peptides Ganoderma lucidum polysaccharide peptides Gastric ulcer Gastric ulcer Oxidative stress Oxidative stress Structural characterization Structural characterization
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| GB/T 7714 | Luo, Hongjian , Zhang, Yukun , Yao, Yang et al. A novel galactoglucan from Ganoderma lucidum ameliorates ethanol-induced gastric ulcers by modulating FAK-MAPK signaling pathway [J]. | CARBOHYDRATE POLYMERS , 2025 , 360 . |
| MLA | Luo, Hongjian et al. "A novel galactoglucan from Ganoderma lucidum ameliorates ethanol-induced gastric ulcers by modulating FAK-MAPK signaling pathway" . | CARBOHYDRATE POLYMERS 360 (2025) . |
| APA | Luo, Hongjian , Zhang, Yukun , Yao, Yang , Zhang, Qiaoling , Lin, Shuqian , Wang, Saizhen et al. A novel galactoglucan from Ganoderma lucidum ameliorates ethanol-induced gastric ulcers by modulating FAK-MAPK signaling pathway . | CARBOHYDRATE POLYMERS , 2025 , 360 . |
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Oyster mushrooms are regarded as one of the most significant edible mushrooms in terms of commercial value because of their rich nutritional profile. Many bioactive extracts from Pleurotus species have been found to exhibit antitumor and antioxidant activities. However, to grow oyster mushrooms in this study, the pasteurized Cenchrus fungigraminus was used as culture material, a type of grass that proliferates and has a high root growth rate. It contains high levels of sugar and protein and yields a large amount of biomass. Because of these characteristics, it is considered an efficient and cost-effective energy crop with various applications, including phytoremediation and fodder production. A pasteurization technique for this grass that is suited for the simplest formulation is simple and cost-effective for growing oyster mushrooms on small farms. This study used pasteurized Cenchrus fungigraminus as a substrate to grow three mushroom species: Pleurotus ostreatus, Pleurotus pulmonarius and Pleurotus florida. The aim was to evaluate their enzyme activities, growth rate, and yields. The findings demonstrated that the average growth rate of three species grown in pasteurized C. fungigraminus was between 25 days and 36 days. Therefore, the mycelium growth rate of P. ostreatus was faster than other pleurotus species in this study. The highest biological efficiency was recorded with P. ostreatus at 78.23%, then P. pulmonarius at 59.88, and lastly, 39.66% P. florida. The changes in five enzyme activities in distinct developmental stages of three different pleurotus species were evaluated. Therefore, the laccase had the highest peak with 13.8 U/g on the 20th day during the growth phase and gradually decreased to the fruiting body stage of P. ostreatus. The expression of manganese peroxidase reached the highest activity of 3.6 U/g in P. ostreatus compared to P. florida and P. pulmonarius on the 10th day. The expression of other enzymes varied between species and developmental phases. The results indicate the usefulness of pasteurized C. fungigraminus for cultivating Pleurotus species and expression enzyme activity in different Pleurotus species.
Keyword ：
biological efficiency biological efficiency Cenchrus fungigraminus Cenchrus fungigraminus enzyme activity enzyme activity nutrients nutrients Pleurotus species Pleurotus species
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| GB/T 7714 | Aimable, Nsanzinshuti , Mediatrice, Hatungimana , Claude, Irambona et al. Enzymatic Activity and Nutrient Profile Assessment of Three Pleurotus Species Under Pasteurized Cenchrus fungigraminus Cultivation [J]. | CURRENT ISSUES IN MOLECULAR BIOLOGY , 2025 , 47 (3) . |
| MLA | Aimable, Nsanzinshuti et al. "Enzymatic Activity and Nutrient Profile Assessment of Three Pleurotus Species Under Pasteurized Cenchrus fungigraminus Cultivation" . | CURRENT ISSUES IN MOLECULAR BIOLOGY 47 . 3 (2025) . |
| APA | Aimable, Nsanzinshuti , Mediatrice, Hatungimana , Claude, Irambona , Biregeya, Jules , Hu, Yingping , Zhou, Hengyu et al. Enzymatic Activity and Nutrient Profile Assessment of Three Pleurotus Species Under Pasteurized Cenchrus fungigraminus Cultivation . | CURRENT ISSUES IN MOLECULAR BIOLOGY , 2025 , 47 (3) . |
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Ulcerative colitis (UC) is a chronic and recurrent gastrointestinal disease that affects millions of humans worldwide and imposes a huge social and economic burden. It is necessary to find safe and efficient drugs for preventing and treating UC. The aim of this study was to determine whether ganoderic acid (GA), the main bioactive components of Ganoderma lucidum, has preventive and therapeutic effect on UC in a dextran sulfate sodium (DSS)-induced UC mouse model. Our experimental results showed that GA significantly ameliorated the body weight loss and disease activity index (DAI) of UC mice. GA significantly restored 11% of the colon length and 69% of the spleen index compared to UC mice. GA significantly decreased the intestinal inflammatory response and improved the barrier function of the intestine by upregulating the tight junction proteins Zonula occludens-1 (ZO-1), occludin and claudin-1. A co-housing experiment showed that gut microbiota accounted for the therapeutic activity of GA on UC, which was confirmed by fecal microbiota transplantation from GA-treated mice to the UC mice. Furthermore, 16S rDNA high-throughput sequencing of fecal bacteria showed that GA significantly enriched the abundance of Lactobacillus, Oscillospira, Odoribacter and Ruminococcus, which were positively correlated with colon length. Furthermore, this study found the functional metabolites, including Indole-3-acetaldehyde (IAAld), Glutamine (Gln) and Glutathione (GSH), reduced barrier damage in the Caco-2 cell model. In conclusion, this study suggests that GA could ameliorate UC by improving intestinal barrier function via modulating gut microbiota and associated metabolites.
Keyword ：
ganoderic acid ganoderic acid gut microbiota gut microbiota intestinal barrier function intestinal barrier function tight junction tight junction ulcerative colitis ulcerative colitis
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| GB/T 7714 | Ye, Yuwei , Abulizi, Abudumijiti , Zhang, Yukun et al. Ganoderic Acid Ameliorates Ulcerative Colitis by Improving Intestinal Barrier Function via Gut Microbiota Modulation [J]. | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , 2025 , 26 (6) . |
| MLA | Ye, Yuwei et al. "Ganoderic Acid Ameliorates Ulcerative Colitis by Improving Intestinal Barrier Function via Gut Microbiota Modulation" . | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 26 . 6 (2025) . |
| APA | Ye, Yuwei , Abulizi, Abudumijiti , Zhang, Yukun , Lu, Feng , An, Yongpan , Ren, Chaoqun et al. Ganoderic Acid Ameliorates Ulcerative Colitis by Improving Intestinal Barrier Function via Gut Microbiota Modulation . | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , 2025 , 26 (6) . |
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Ganoderma polysaccharides (peptides) are essential bio-macromoleculars that determine the quality of Ganoderma. Their molecular weight,distribution and content are influenced by factors such as origin, strain, cultivation conditions, harvesting period and processing methods. In this study, we established a molecular weight specific chromatogram using high performance gel permeation chromatography (HPGPC) for Ganoderma glycopeptide and assessed its potential applications. The results revealed consistent molecular weight distributions across different cultivation conditions, with 6-8 characteristic peaks showing similarity values exceeding 0.93. The average molecular weight of common peaks was highest during the budding stage and lowest in the mature stage. Ganoderma lucidum (GL) exhibited higher molecular weights compared to Ganoderma sinense (GS). Moreover, both molecular weight and Ganoderma glycopeptides decreased with prolonged growth periods. The content of GL-PPSQ2 was significantly higher in the budding (1.63 +/- 0.15%) and cap-opening stages (1.51 +/- 0.12%) compared to the mature stage (1.31 +/- 0.05%). Chemometrics analysis revealed distinct molecular weight profiles for different growth stages and varieties. Additionally, the HPGPC method was successfully applied to detect adulteration in Ganoderma extracts, identifying excipients such as maltodextrin and dextran. This study underscores the importance of molecular weight distribution and glycopeptide content as key quality control indicators, providing a rapid and reliable tool for ensuring the authenticity and quality of Ganoderma extracts in the market.
Keyword ：
Adulteration Adulteration Ganoderma Ganoderma Ganoderma extracts Ganoderma extracts Gel permeation chromatography Gel permeation chromatography Glycopeptide Glycopeptide Molecular weight specific chromatogram Molecular weight specific chromatogram
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| GB/T 7714 | Luo, Hongjian , Lin, Shuqian , Lin, Zhanxi et al. Establishment of molecular weight specific chromatogram of Ganoderma glycopeptide and its application in extract [J]. | FOOD BIOSCIENCE , 2025 , 66 . |
| MLA | Luo, Hongjian et al. "Establishment of molecular weight specific chromatogram of Ganoderma glycopeptide and its application in extract" . | FOOD BIOSCIENCE 66 (2025) . |
| APA | Luo, Hongjian , Lin, Shuqian , Lin, Zhanxi , Lu, Haining , Ma, Ang , Lin, Dongmei . Establishment of molecular weight specific chromatogram of Ganoderma glycopeptide and its application in extract . | FOOD BIOSCIENCE , 2025 , 66 . |
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Waterlogging, or excessive accumulation of water in the soil, poses significant stress to riparian ecosystems and agroforestry, especially with increasing global rainfall. Cenchrus fungigraminus is a vital agricultural resource, biomaterial, and super-energy plant with high resistance and adaptability. This study examined its morphological and physiological responses under root and above-ground waterlogging for up to 30 days. Results showed that waterlogging significantly inhibited growth, reducing membrane permeability, and root activity, and accelerating leaf senescence (P < 0.05). Despite this, C. fungigraminus achieved 100 % survival after 30 days of waterlogging. The plant adapted to the hypoxic environment by enhancing oxygen channels through cortex cell loosening, lysigenous tissue formation, and adventitious root development. It also activated defense mechanisms, increasing the activities of antioxidant enzymes (SOD, POD, and CAT), levels of non-enzymatic antioxidants (AsA and GSH), osmotic regulators (SS, SP, and Pro), and anaerobic respiratory enzymes (PDC, ADH, and LDH), and hormones (ABA, IAA, GA, and ETH). Under two levels of waterlogging depth, the plant initially adopted the LowO2 escape strategy (LOES), but over time, it transitioned to the Low-O2 quiescence strategy (LOQS), while still retaining some features of the LOES. Our results revealed that C. fungigraminus demonstrates strong adaptability to waterlogging, especially in response to root waterlogging. By employing anatomical adjustments and exceptional cellular defense mechanisms, the species effectively mitigates damage, establishing itself as an excellent forage grass for slope protection under waterlogged conditions. These results offer valuable guidance for selecting waterlogging-tolerant species to restore and rehabilitate degraded riparian ecosystems in the Yellow River Basin, optimize land use in waterlogging-prone areas, and advance the genetic improvement of waterlogging tolerance in other forage varieties.
Keyword ：
Anatomy Anatomy Cenchrus fungigraminus Cenchrus fungigraminus Growth strategy Growth strategy Morphology Morphology Physiology Physiology Waterlogging Waterlogging
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| GB/T 7714 | Song, Simeng , Zhou, Hengyu , Luo, Yuan et al. Effects of waterlogging at different duration on growth and physiological characteristics of Cenchrus fungigraminus [J]. | ENVIRONMENTAL AND EXPERIMENTAL BOTANY , 2025 , 231 . |
| MLA | Song, Simeng et al. "Effects of waterlogging at different duration on growth and physiological characteristics of Cenchrus fungigraminus" . | ENVIRONMENTAL AND EXPERIMENTAL BOTANY 231 (2025) . |
| APA | Song, Simeng , Zhou, Hengyu , Luo, Yuan , Yu, Shikui , Su, Dewei , Zheng, Dan et al. Effects of waterlogging at different duration on growth and physiological characteristics of Cenchrus fungigraminus . | ENVIRONMENTAL AND EXPERIMENTAL BOTANY , 2025 , 231 . |
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The traditional cultivation of Dictyophora indusiata mostly uses bamboo as a material, which is expensive, limited by region, and negatively affects bamboo forest ecosystems. Herein, field experiments were conducted to investigate the effect of cultivating D. indusiata under various treatments. A multidisciplinary analytical approach incorporating one-way analysis of variance, Redundancy analysis, and partial least squares path modelling were employed to systematically assess cultivation impacts across multiple biological matrices. The evaluation framework encompassed fruiting bodies, soil physicochemical properties, enzyme activities, phenolic acids, and microbial dynamics. All treatments significantly improved soil fertility, with the cultivation of Cenchrus fungigraminus and sawdust combined with seafood mushroom spent mushroom substrate (SMS) as padding exhibiting the most substantial increased in total nitrogen, inorganic nitrogen, organic matter, and organic carbon compared to that before cultivation. Soil enzyme activity associated with D. indusiata cultivation increased S-ACP and decreased S-CAT and S-UE levels. The total phenolic acid content in the soil increased following D. indusiata cultivation. Moreover, a single application of 25 mg/L ferulic acid, 20 mg/L p-hydroxybenzoic acid, or 250 mg/L p-coumaric acid promoted D. indusiata mycelial growth and enhanced the proliferation of pathogenic microorganisms. Cultivating D. indusiata also induced changes in both abundance and structure within soil microbial communities. Reductions in the abundance of beneficial bacteria, along with predictions related to microbial functions, occurred more gradually and stably within the SMS treatments. In conclusion, microbial changes were gradual within the SMStreated, indicating that SMS application can stabilise the structure of soil microbial communities.
Keyword ：
Cenchrus fungigraminus Cenchrus fungigraminus Dictyophora indusiata Dictyophora indusiata Seafood mushroom spent substrate Seafood mushroom spent substrate Soil environment Soil environment Soil phenolic acid Soil phenolic acid
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| GB/T 7714 | Lei, Yufang , Jiang, Fengju , Di, Xiaoyue et al. Cultivating Dictyophora indusiata with Cenchrus fungigraminus and seafood mushroom spent substrate enhanced soil nutrient accumulation and microbial community stabilisation [J]. | ENVIRONMENTAL TECHNOLOGY & INNOVATION , 2025 , 38 . |
| MLA | Lei, Yufang et al. "Cultivating Dictyophora indusiata with Cenchrus fungigraminus and seafood mushroom spent substrate enhanced soil nutrient accumulation and microbial community stabilisation" . | ENVIRONMENTAL TECHNOLOGY & INNOVATION 38 (2025) . |
| APA | Lei, Yufang , Jiang, Fengju , Di, Xiaoyue , Lin, Dongmei , Ling, Panpan , Zhang, Yao et al. Cultivating Dictyophora indusiata with Cenchrus fungigraminus and seafood mushroom spent substrate enhanced soil nutrient accumulation and microbial community stabilisation . | ENVIRONMENTAL TECHNOLOGY & INNOVATION , 2025 , 38 . |
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Soil salinization and alkalization are serious global challenges that adversely affect crop growth and yield. In this study, six genotypes of giant reed (Arundo donax) seedlings (LvZhou_No.1, LvZhou_No.3, LvZhou_No.6, LvZhou_No.11, LvZhou_No.12 and LvZhou_Var.) originating from different regions of China and Rwanda were utilized as experimental materials. This study aimed to investigate the physiological and biochemical responses of various genotypes to saline-alkali stress and to identify stress-tolerant resources. A mixture saline-alkali solution with a molar ratio of NaCl: Na2SO4: NaHCO3: Na2CO3 = 1:1:1:1 was prepared at three concentrations (75, 150 and 225 millimolar (mM)) for a 7-day pot experiment. Growth and physiological indices were measured at the seedling stage, and salt tolerance was evaluated accordingly. The results indicated the following: the growth indices were significantly reduced across seedlings of all genotypes when the concentration of stress exceeded 150 mM (p < 0.05). There was no significant difference in chlorophyll content (SPAD value) and maximum photochemical efficiency of PS II (F-v/F-m) with increasing saline-alkali stress. However, the photosynthetic rate (P-n), stomatal conductance (G(s)) and transpiration rate (T-r) exhibited decreasing trends, reaching their lowest levels at 225 mM. In contrast, the intercellular CO2 concentration (C-i) value decreased to its lowest at 150 mM but increased at 225 mM. Relative electrical conductivity (REC) and the contents of malondialdehyde (MDA), proline (Pro) and soluble sugar (SS) increased progressively with higher stress concentrations. The activities of superoxide dismutase (SOD), peroxidase (POD) and catalase (CAT) were significantly enhanced at stress concentrations above 150 mM. The saline-alkali tolerance of A. donax seedlings was comprehensively evaluated using principal component analysis and membership function analysis based on 15 parameters. The results indicate that P-n, T-r and G(s) are effective physiological indicators for assessing saline-alkali tolerance of A. donax seedlings. The six genotypes were ranked for saline-alkali tolerance as follows: LZ_No.1 > LZ_No.11 > LZ_No.12 > LZ_Var. > LZ_No.3 > LZ_No.6. This indicates that LZ_No.1 shows the highest resistance to saline-alkali stress, whereas LZ_No.6 is the most severely affected, classifying it as a salinity-sensitive genotype. In conclusion, LZ_No.1 exhibits robust saline-alkali tolerance and represents a valuable germplasm resource for improving saline-alkali tolerance in A. donax propagation. The results not only support the development of resilient plants for saline-alkali environments but also offer insights into the mechanisms of salinity tolerance.
Keyword ：
Arundo donax Arundo donax correlation analysis correlation analysis physiological and biochemical responses physiological and biochemical responses saline-alkali stress saline-alkali stress saline-alkali tolerance evaluation saline-alkali tolerance evaluation
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| GB/T 7714 | Cai, Yangxing , Cao, Xiuming , Liu, Bin et al. Saline-Alkali Tolerance Evaluation of Giant Reed (Arundo donax) Genotypes Under Saline-Alkali Stress at Seedling Stage [J]. | AGRONOMY-BASEL , 2025 , 15 (2) . |
| MLA | Cai, Yangxing et al. "Saline-Alkali Tolerance Evaluation of Giant Reed (Arundo donax) Genotypes Under Saline-Alkali Stress at Seedling Stage" . | AGRONOMY-BASEL 15 . 2 (2025) . |
| APA | Cai, Yangxing , Cao, Xiuming , Liu, Bin , Lin, Hui , Luo, Hailing , Liu, Fengshan et al. Saline-Alkali Tolerance Evaluation of Giant Reed (Arundo donax) Genotypes Under Saline-Alkali Stress at Seedling Stage . | AGRONOMY-BASEL , 2025 , 15 (2) . |
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Malnutrition in underdeveloped regions is exacerbated by the lack of accessible, nutrient-dense foods and energy-intensive agricultural practices. This study introduces a sustainable non-sterile cultivation method for Pleurotus sapidus (an oyster mushroom species) using fresh Pennisetum giganteum (Giant Juncao grass), a fast-growing C4 grass cultivated on marginal soils. Unlike conventional sterilization-dependent approaches, our method employs lime-saturated water (LW, 4 mLg-1) to pretreat fresh grass, eliminating the need for drying; a critical advantage in humid regions where biomass degradation occurs rapidly. Coupled with optimized substrate composition (2% CaO, 0.5% corn flour), this strategy achieved robust mycelial growth (0.53 cmd-1) and high biological efficiency (112.78%). LW treatment altered substrate metabolites and reduced soluble nutrients. L-malic acid and soluble sugars promoted P. sapidus growth, whereas amino acids, available nitrogen (N), phosphorus (P) and potassium (K), and lactic acid inhibited its growth. The Mucor circinelloides was identified as a key contaminant. This scalable strategy transforms underutilized lignocellulosic biomass into nutrient-rich food, aligning with SDG 2 (Zero Hunger) and SDG 12 (Responsible Consumption and Production).
Keyword ：
food security food security fresh Pennisetum giganteum fresh Pennisetum giganteum marginal-land agriculture marginal-land agriculture non-sterile mushroom cultivation non-sterile mushroom cultivation SDGs SDGs
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| GB/T 7714 | Zhang, Yulong , Lu, Yiting , Li, Zhijun et al. Non-sterile substrate cultivation of oyster mushrooms on fresh Giant Juncao Grass: a scalable strategy for sustainable nutrition in underdeveloped regions [J]. | FRONTIERS IN SUSTAINABLE FOOD SYSTEMS , 2025 , 9 . |
| MLA | Zhang, Yulong et al. "Non-sterile substrate cultivation of oyster mushrooms on fresh Giant Juncao Grass: a scalable strategy for sustainable nutrition in underdeveloped regions" . | FRONTIERS IN SUSTAINABLE FOOD SYSTEMS 9 (2025) . |
| APA | Zhang, Yulong , Lu, Yiting , Li, Zhijun , Xie, Mingjun , Wen, Fengmei , Li, Jing et al. Non-sterile substrate cultivation of oyster mushrooms on fresh Giant Juncao Grass: a scalable strategy for sustainable nutrition in underdeveloped regions . | FRONTIERS IN SUSTAINABLE FOOD SYSTEMS , 2025 , 9 . |
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Antler-shaped Ganoderma lucidum (G. lucidum) is cultivated using specialized methods with high content of active ingredients. In this study, we employed a widely-targeted metabolomics to analyze the metabolic regulation in various parts of antler-shaped G. lucidum. Using ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS), we identified a total of 1016 metabolites and 615 differential metabolites (DMs) across three parts. KEGG pathway analysis found that 353 metabolic pathways were involved in the growth process. The quantitative results revealed that the undifferentiated cap region exhibited the highest content of triterpenes, while the basal region contained higher levels of polysaccharides. Network pharmacology identified 22 key targets from saccharide-related DMs, and 19 key targets from terpenoid-related DMs. These findings demonstrate that antler-shaped G. lucidum can be harvested and processed in a segmented manner to optimize the extraction of bioactive compounds, providing valuable insights for its scientific utilization in nutritional supplements and healthcare.
Keyword ：
Antler-shaped Ganoderma lucidum Antler-shaped Ganoderma lucidum Network pharmacology Network pharmacology Saccharides Saccharides Triterpenes Triterpenes Wide targeted metabolomics Wide targeted metabolomics
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| GB/T 7714 | Luo, Hongjian , Lin, Dongmei , Su, Dewei et al. Wide-target metabolomics and network pharmacology reveal metabolic regulation and targets of bioactive compounds in antler-shaped Ganoderma lucidum [J]. | FOOD BIOSCIENCE , 2025 , 71 . |
| MLA | Luo, Hongjian et al. "Wide-target metabolomics and network pharmacology reveal metabolic regulation and targets of bioactive compounds in antler-shaped Ganoderma lucidum" . | FOOD BIOSCIENCE 71 (2025) . |
| APA | Luo, Hongjian , Lin, Dongmei , Su, Dewei , Luo, Zongzhi , Wang, Lianfu , Lu, Guodong et al. Wide-target metabolomics and network pharmacology reveal metabolic regulation and targets of bioactive compounds in antler-shaped Ganoderma lucidum . | FOOD BIOSCIENCE , 2025 , 71 . |
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